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Nioxin

System 3 Leave In Treatment

Scalp treatment

  • Scalp treatment
  • Sulfate-free
  • Silicone-free
  • Curly-method
  • Not cruelty-free · PETA-listed
Size6.76 fl ozmost listed · 2 sizes
Priceabout $43 Good valuecommonly seen · 6.76 oz
Price / oz$6.36/ozat 6.76 oz
Where to buy4 stores · 2 sizes

Scent:

The ingredient list declares fragrance. What it smells of is not stated, and we do not guess.

Manufacturer page: nioxin.com

Personal fit

Is this right for you?

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Priced with its peers

$6.36/oz at 6.76 oz — less than 53% of the 152 scalp treatments , which mostly run $3.22–20.64/oz.

Price and stores

Great for

Fine hairthat flattens under most products
Silicone-free routinesno silicones appear in the list
Very dry hairno fast-drying alcohol in the list
Easy to findsold through several channels

Maybe skip if

this product carries a scent
Vegan and cruelty-freeour record does not support both claims here
Tight budgetsit sits in the upper price tiers

Whether this much richness is right for you depends on your strand thickness, porosity, and how easily your hair flattens — that is what the consultation works out.

What the formula actually does

Read from the label, not the marketing

Each row says where it comes from: F means we derived it from this product’s own ingredient list, S means it is a claim the brand makes that the formula neither confirms nor contradicts.

Slip and detangling Little

Nothing here is built to reduce combing force.

Oils and butters None

No oils or butters in the list.

Weight on the hair Light

Water-first and light: unlikely to flatten fine hair.

Water-binding (humectants) Moderate

Humectants in the working part of the formula.

Protein Minor

Protein appears, low enough to be a supporting ingredient.

Needs detergent to remove No

Nothing here needs a detergent wash to remove.

Hard-water defence Chelators present

Chelators are present — they bind hard-water and pool minerals.

Fragrance Present

Fragrance is listed; it sits below the working ingredients.

from the formula stated by the brand reported by reviewers Scale: 1 dot low · 5 dots high, within this product type.

Ingredients that matter

The ingredients that change a decision

The workhorse ingredients plus anything lower down that changes a decision. These chips name what an ingredient does — they are not safety scores, and no ingredient here is rated good or bad on its own.

IngredientWhat it doesWhy it mattersChip
WaterAqua/Water/Eau solvent The base everything else is dissolved in Neutral
Niacinamide vitamin A marketed vitamin addition Detangles
Caffeine active The over-the-counter active Active
Phenoxyethanol preservative Keeps the product from spoiling Stabilizes
Sodium Benzoate preservative Keeps the product from spoiling Stabilizes
Benzyl Alcohol preservative Keeps the product from spoiling Stabilizes
Acrylates/C10-30 Alkyl Acrylate Crosspolymer thickener Adjusts the texture Holds
Polysorbate 80 emulsifier Stabilises the mix Stabilizes
FragranceParfum/Fragrance fragrance The scent Fragrance
Mentha Arvensis Leaf Oil fragrance The scent Fragrance
Mentha Piperita (Peppermint) Oil botanical extract A trace plant extract Fragrance
Limonene fragrance The scent Fragrance
What the list leaves out, and what it carriesThe list carries no sulfates, silicones, or drying alcohols. Fragrance is on the label. Hard-water chelators are present.
Full ingredient list (41)

US labelling rules put ingredients above 1% in descending order of amount; below 1% they may be listed in any order. Annotations keep three readings separate: the ingredient's general function, its role in this product type, and what its position can support.

  • 1 Water · Aqua/Water/Eau
    General function

    The base of almost every rinse-off and cream hair product. It carries everything else and is normally the first ingredient on the label.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    • solvent
  • 2 Niacinamide
    General function

    Vitamin B3, used in scalp products for conditioning claims.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    May suitFrizz-prone, damaged, or high-friction hair

    Deposits a lubricating layer that makes combing easier, which is most of what stops mechanical damage adding to frizz.

    PubChem
    • vitamin
    • conditioning agent
  • 3 Caffeine
    General function

    Included in scalp and thickening products for label appeal. Evidence for applied caffeine changing hair growth is limited.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    PubChem
    • active
  • Below about this point, order stops being meaningful — these are typically used at 1% or less.
  • 4 Phenoxyethanol
    General function

    The most common modern preservative; it keeps the product free of bacteria and mould. It sits well below 1% of the formula.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    PubChem
    • preservative
  • 5 Sodium Benzoate
    General function

    A food-grade preservative that works only in acidic formulas, which is why it usually appears alongside citric acid.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    PubChem
    • preservative
  • 6 Benzyl Alcohol
    General function

    A preservative and solvent that also occurs naturally in some essential oils.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    PubChem
    • preservative
    • solvent
  • 7 Acrylates/C10-30 Alkyl Acrylate Crosspolymer
    General function

    A gel-forming thickener that also keeps oils suspended. It contributes a little hold.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitClimate-sensitive or frizz-prone hair

    A set polymer film is a physical barrier to humidity, so a style keeps its shape longer in damp conditions.

    May suitMaximum-hold styling

    Synthetic film formers dry into a continuous film, which is what holds a shape against movement and against humid air.

    DependsBuild-up-sensitive routines

    Some acrylate copolymers rinse with water and some need a detergent; the label alone does not say which one a formula used.

    • thickener
    • polymer
    • film former
  • 8 Polysorbate 80
    General function

    A solubiliser that dissolves fragrance and oils into water so the product stays clear.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    • emulsifier
    • solubilizer
  • 9 Polysorbate 60
    • emulsifier
    • solubilizer
  • 10 Acetamide MEA
    General function

    A humectant that also improves slip, used in conditioners and styling creams.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitFrizz-prone, damaged, or high-friction hair

    Deposits a lubricating layer that makes combing easier, which is most of what stops mechanical damage adding to frizz.

    May suitVery dry or highly damaged hair

    Humectants bind water into the strand, and water — not oil — is what makes dry hair flexible instead of brittle.

    DependsClimate-sensitive or frizz-prone hair

    A humectant follows the air: it holds water in humid conditions and can give it up in very dry ones. Climate decides what it does more than the label does.

    PubChem
    • humectant
    • conditioning agent
  • 11 Triethanolamine
    General function

    A base used in trace amounts to neutralise acidic polymers so a gel thickens.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    DependsFrizz-prone, damaged, or high-friction hair

    pH adjusters are how a formula is brought to a chosen acidity, and an acidic formula keeps the cuticle lying flatter than an alkaline one. Which way this one moves the pH depends on the formula, and the finished pH is not on the label.

    PubChem
    • pH adjuster
  • 12 PEG-23M
    • polymer
    • thickener
    • binder
  • 13 Tetrasodium EDTA
    General function

    Binds the metal ions in hard water so they cannot dull hair or destabilise the formula.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitBuild-up-sensitive routines

    Binds the calcium and magnesium in hard water, which is what stops mineral deposits accumulating on the strand wash after wash.

    May suitGray, silver, or brass-prone hair

    Copper and iron carried in tap water deposit on the strand and read as a dull, warm cast on gray or light hair. A chelator holds those metals in solution so the wash carries them off.

    PubChem
    • hard-water chelator
  • 14 Propylene Glycol
    General function

    A small humectant and solvent that keeps formulas stable and helps active ingredients spread.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitFine or easily flattened hair

    Light and water-binding rather than oily, so it hydrates without contributing weight.

    May suitVery dry or highly damaged hair

    A small water-binding solvent. It holds moisture and helps the rest of the formula spread evenly over the strand.

    DependsClimate-sensitive or frizz-prone hair

    A humectant follows the air: it holds water in humid conditions and can give it up in very dry ones. Climate decides what it does more than the label does.

    PubChem
    • humectant
    • solvent
  • 15 Methyl Nicotinate
  • 16 Fragrance · Parfum/Fragrance
    General function

    An undisclosed blend of scent ingredients. Regulations let it stay unlisted, so a fragrance-free product is the only way to be certain what is not in it.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May not suitFragrance-sensitive routines

    Declared fragrance. On a fragrance-sensitive routine this is the line that decides it, wherever it sits on the label.

    • fragrance
    • declared fragrance
  • 17 Mentha Arvensis Leaf Oil
    General function

    Cornmint oil, used for a cooling sensation and mint scent.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May not suitFragrance-sensitive routines

    Declared fragrance. On a fragrance-sensitive routine this is the line that decides it, wherever it sits on the label.

    • fragrance
    • botanical extract
  • 18 Mentha Piperita (Peppermint) Oil
    General function

    Peppermint essential oil, used for scent and the cooling feeling on the scalp.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May not suitFragrance-sensitive routines

    Essential oils are fragrance. Several carry constituents on the EU list of declared fragrance allergens, so a label with no fragrance line can still be a scented product.

    • botanical extract
    • essential oil
    • fragrance
  • 19 PEG-30 Dipolyhydroxystearate
  • 20 Trideceth-6
    • emulsifier
    • solubilizer
  • 21 Limonene
    General function

    A citrus-smelling fragrance component that EU rules require to be named separately because some people react to it.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May not suitFragrance-sensitive routines

    One of the 26 scent components the EU requires to be named individually above a threshold. It is named because it is a known contact allergen, not because it is unusual.

    PubChem
    • fragrance
    • named fragrance allergen
  • 22 Camellia Sinensis (Green Tea) Leaf Extract · Camellia Sinensis Leaf Extract
    • botanical extract
    • antioxidant
  • 23 Silica
    General function

    A fine mineral powder that absorbs oil and adds grip. It is what makes texture powders and matte pastes feel dry to the touch.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitFine or easily flattened hair

    A dry powder takes up oil and adds friction between strands, which is most of what root lift in fine hair actually is.

    PubChem
    • powder
    • thickener
    • mineral
  • 24 Cystine Bis-PG-Propyl Silanetriol
    General function

    A cystine derivative modified to bind more firmly to the strand, used in strengthening formulas.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitVery dry or highly damaged hair

    Amino acids are the smallest protein fraction and bind water as well, so they add far less stiffness than a hydrolysed protein does.

    DependsProtein-sensitive hair

    The lightest option in the protein family, but still protein — worth watching if protein reliably stiffens your hair.

    • amino acid
    • protein
  • 25 Biotin
    • vitamin
  • 26 Tocopheryl Acetate
    • antioxidant
    • vitamin
  • 27 Lecithin
    General function

    A soy- or sunflower-derived lipid that helps conditioning ingredients spread evenly on the strand.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitFrizz-prone, damaged, or high-friction hair

    Emollients fill and smooth the surface of the strand, which lowers the friction that lifts the cuticle and reads as roughness.

    PubChem
    • emulsifier
    • emollient
  • 28 Foeniculum Vulgare (Fennel) Fruit Extract
    • botanical extract
  • 29 Acer Saccharum (Sugar Maple) Extract
    • botanical extract
  • 30 Citrus Limon (Lemon) Peel Extract
    • botanical extract
  • 31 Saccharum Officinarum/Sugar Cane Extract/Extrait de canne à sucre
  • 32 Vaccinium Myrtillus Leaf Extract
    • botanical extract
  • 33 Faex Extract/Yeast Extract/Extrait de levure
  • 34 Propylparaben
    • paraben
    • preservative
  • 35 Citrus Aurantium Dulcis (Orange) Fruit Extract
    • botanical extract
  • 36 BHT
    • antioxidant
  • 37 Maltodextrin
    General function

    A starch fragment that soaks up oil and water, which is what puts it in dry shampoos. It also carries spray-dried plant extracts and leaves a light film.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitFine or easily flattened hair

    Takes up oil at the root, which is where fine hair goes flat first.

    May suitMaximum-hold styling

    Film formers are what hold a style: they dry into a connected film across the strands so the shape resists movement.

    DependsCurls or waves needing flexible hold

    How rigid the finish is depends on which polymer it is and what the formula pairs with it, not on there being one.

    • absorbent
    • film former
    • binder
  • 38 Methylparaben
    • paraben
    • preservative
  • 39 Potassium Sorbate
    • preservative
  • 40 Ethylparaben
    • paraben
    • preservative
  • 41 Butylparaben
    • paraben
    • preservative

What the whole list adds up to

  • 8 preservatives
  • 8 botanical extracts
  • 4 emulsifiers
  • 4 fragrances
  • 4 parabens
  • 3 solvents
  • 3 vitamins
  • 3 thickeners
  • 3 solubilizers
  • 3 antioxidants
  • 2 conditioning agents
  • 2 polymers
  • 2 film formers
  • 2 humectants

Ingredient list captured 2026-09-11. Formulas change — check the package in your hand when an ingredient matters to you.

Price · 6.76 oz

Commonly seen about $43 Midpoint $43 · 3 stores · checked Sep 13
Good value under $77 Under $11.38/oz it costs less than three-quarters of the 8 products we score as doing the same job

Usually a good value. Most stores sell it under the $77 line, and products that do this job typically go for about $137 at this size.

Sizes

3.38 oz
$27
$7.99/oz
6.76 ozmost listed
$43
$6.36/oz

The 6.76 oz costs 20% less per ounce than the 3.38 oz.

Show the price ladder
Where we’ve seen it4 listings · 3 stores

6.76 ozmost listedBest per ounce

  • Nioxin US
    $43.00
    6.76 oz · $6.36/oz
    Sep 11Lowest per oz
  • Amazon
    $43.00
    6.76 oz · $6.36/oz
    Sep 13
  • Ulta Beauty
    $43.00
    6.7 oz · $6.42/oz
    Sep 11

3.38 oz

  • Amazon
    $27.00
    3.38 oz · $7.99/oz
    Sep 13Lowest per oz

Sorted by price per ounce. Dated observations from our research, not live prices. Direct store pages, no affiliate links. We don’t sell this product.

How we work this out
  1. 6.76 oz is the size stores list most often; every comparison on this page is made at it. Other sizes are shown in the Sizes row and the store list.
  2. Commonly seen is the middle half of current prices for the 6.76 oz at recognised stores — the cheapest quarter and the dearest quarter are left out, so one sale or one overpriced listing can’t move it.
  3. Good value under $77 comes from the 8 products we score as doing the same job as this one. A quarter of them cost less than $11.38/oz; at 6.76 oz that is $77. Under that line you are paying less than most of them.
  4. Each size is guarded on its own, so a multipack or a marketplace listing at one size cannot move another.
  5. About $137 is what those same products typically cost at this size — the midpoint of their prices per ounce, scaled to 6.76 oz.

Formula

Formula score
3 of 10

Mid-range per ounce for a shorter formula: there is no conditioning agents up front here.

How the score is counted
  • Costs less per ounce than 53% of the 152 scalp treatments we’ve priced
  • No conditioning agents up front in the formula
  • No oils or butters in the working zone either
  • Salon tier, sold at Salons and Specialty beauty
  • Conditioning agents up frontWhat makes wet hair comb through.3 pts
  • Oils or butters in the working zoneSoftens the strand rather than just coating it.2 pts
  • Slip for detanglingReduces the force it takes to comb wet hair.2 pts
  • A humectantBinds water into the hair.1 pt
  • A pH adjusterBrings the formula to the acidic pH hair prefers.1 pt
  • Fragrance kept out of the top eightScent as a finishing touch, not a major share.1 pt

The formula score is completeness for the job: the share of the systems this product type is normally built around that we can find in this list, weighted. It is not efficacy, not quality, and it never compares across product types.

Does the same job

Same derived functions — what it cleans, conditions, coats or holds — at a lower cost per ounce. Scent, texture and where you buy it can still differ.

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  • Alcohol-free
· Same function
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  • Fragrance-free
  • Lightweight
  • Silicone-free
· Close function
Function
  • Water-binding (humectants)
  • Film formers
Also
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Function
  • Film formers
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See more alternatives in the product library

These are functional neighbours, not personal recommendations — they are close on formula, not chosen for anyone. Get the one that fits your hair, routine, and budget

Suits every hair pattern

Final decision

Should you buy it?

Good for the right person
Best user

Fine or easily-flattened hair, looking for something that will not weigh hair down and a silicone-free formula

Biggest tradeoff

Less suited to anyone sensitive to fragrance, vegan and cruelty-free shopping, or people shopping on a budget

Best alternative if not

Nothing in our library matches it closely at a lower price.

We do not sell products or take placement fees. This page states what the formula and the prices show; the consultation is what matches it to a person.

Claims check

What the brand says, against what the formula shows

Claims are quoted from the brand. We only mark one supported, partly supported, or conflicting when the ingredient list actually speaks to it; everything else stays "stated by the brand", which is not a criticism — most claims simply cannot be read off a label.

1
SupportedBacked by ingredients
1
Partly supportedSome supporting logic
0
Stated by brandNo clear evidence
0
Potential conflictFormula works against claim
Thickens the hair

It reads light on the strand, which is what volume claims depend on.

  • Acrylates/C10-30 Alkyl Acrylate Crosspolymer
  • PEG-23M
Supported

Leaves room for lift.

Nourishes the scalp

Humectants and emollients are present, but lower in the list than the claim implies.

  • Acetamide MEA
  • Propylene Glycol
Partly supported

Some hydration, at a low level.

How to read this

We look at the first 10–15 ingredients and what they do in a formula — not marketing. If the list doesn't speak to a claim, we don't assume.

More from Nioxin

How this page was made

  • Everything above is generated from our researched product record — identity, the ingredient list as printed, the brand's own claims, dated price observations, and review themes written in our researchers' own words. No part of this page is written per product.
  • The value band is a fixed label over two stored numbers: this product’s cost per ounce as a percentile of every product of this type we have priced, each at the size it is most often sold in, and how many products we score as doing the same job cost at least a quarter less per ounce.
  • Both scores out of ten are defined on this page. The formula score is completeness for the job, computed from a fixed per-format checklist shown beneath the gauge; the price score is cost per ounce against every product of this type we have priced.
  • The "Is this right for you?" panel reads only your own consultation answers, and it applies exactly the filters our recommendation engine applies. It is computed when you load the page and is never stored on it.
  • 6 sources consulted for this product (2 manufacturer or regulatory, 1 retailer, 3 editorial), last checked 2026-09-13.
  • Ingredient references are linked for 8 of 14 product-aware annotations on this page. Fit notes are conditional formulation guidance, not a conclusion about the finished product or about you.
  • We have not tested this product in a lab and we do not physically test your hair. Formula readings come from the ingredient list; behaviour claims are labelled as the brand's.
  • Ingredient order tells you relative amount only above roughly 1%. Prices are observations on the dates shown and change without notice.
  • Ingredient names link to our ingredient library, where each entry shows what it does, which product types use it, and where it usually sits on a label across everything we have researched.
  • This is cosmetic information, not medical advice, and nothing here diagnoses or treats a health condition.
  • Formula readings: derivation v22. Record last updated 2026-09-11.