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Nioxin

Scalp Relief Shampoo

Shampoo / Everyday cleanser, balanced

  • Shampoo
  • Sulfate-free
  • Silicone-free
  • Protein-free
  • Not cruelty-free · PETA-listed
Size6.76 fl ozmost listed · 2 sizes
Priceabout $27commonly seen · 6.76 oz · from $1.86/oz in the 33.8 oz
Price / oz$3.99/ozat 6.76 oz
Where to buy6 stores · 2 sizes

Scent:

The ingredient list declares fragrance. What it smells of is not stated, and we do not guess.

Manufacturer page: nioxin.com

Personal fit

Is this right for you?

Complete the consultation to see exactly how well this product fits your hair and your goals. With 2,400+ products in our library we can match exactly the right products to you.

  • In 10 minutes we can identify your exact hair condition and traits.
  • Every product matched against your hair across the 22 factors we check.
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  • Find products that do the same job at a lower cost.
  • Your goals, scalp, damage history, water, budget, and scent preferences all shape your plan.

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Same job for less elsewhere

$3.99/oz at 6.76 oz — more than 85% of the 817 shampoos , which mostly run $0.81–3.01/oz.

View alternatives

Great for

Colour-treated hairthat fades faster in a sulfate wash
Protein-sensitive hairthat stiffens when protein is added
Curly-method routinesno sulfates and no water-insoluble silicones
Fine hairthat flattens under most products
Silicone-free routinesno silicones appear in the list
Very dry hairno fast-drying alcohol in the list

Maybe skip if

this product carries a scent
Hair that needs proteinthere is none in this list
Hard waterno chelator here to bind the minerals
Vegan and cruelty-freeour record does not support both claims here
Tight budgetsit sits in the upper price tiers

Whether this much cleansing is right for you depends on how fast your scalp oils, how much product you layer, and your water — that is what the consultation works out.

What the formula actually does

Read from the label, not the marketing

Each row says where it comes from: F means we derived it from this product’s own ingredient list, S means it is a claim the brand makes that the formula neither confirms nor contradicts.

Cleansing strength Moderate

Removes oil and product; leaves some conditioning behind.

Expected lather Moderate

An ordinary shampoo lather.

Slip and detangling Moderate

Conditioning agents are present, lower in the list.

Water-binding (humectants) Moderate

Humectants in the working part of the formula.

Scalp active None

No over-the-counter scalp active.

Hard-water defence None

No chelating agent in the list.

Needs detergent to remove No

Nothing here needs a detergent wash to remove.

Protein None

No protein or amino acids in the list.

Fragrance Prominent

Fragrance sits in the first eight ingredients — a larger share of the formula.

from the formula stated by the brand reported by reviewers Scale: 1 dot low · 5 dots high, within this product type.

Ingredients that matter

The ingredients that change a decision

The workhorse ingredients plus anything lower down that changes a decision. These chips name what an ingredient does — they are not safety scores, and no ingredient here is rated good or bad on its own.

IngredientWhat it doesWhy it mattersChip
WaterAQUA/WATER/EAU solvent The base everything else is dissolved in Neutral
Cocamidopropyl Betaine amphoteric cleanser Cleanses
Sodium Methyl Oleoyl Taurate mild anionic cleanser Cleanses
Sodium Lauroyl Sarcosinate mild anionic cleanser Cleanses
FragrancePARFUM/FRAGRANCE fragrance The scent Fragrance
Phenoxyethanol preservative Keeps the product from spoiling Stabilizes
Sodium Benzoate preservative Keeps the product from spoiling Stabilizes
Citric Acid pH adjuster Fine-tunes the pH pH balancer
What the list leaves out, and what it carriesThe list carries no sulfates, silicones, or drying alcohols. No protein — a moisture formula, not a repair one. Fragrance is on the label.
Full ingredient list (18)

US labelling rules put ingredients above 1% in descending order of amount; below 1% they may be listed in any order. Annotations keep three readings separate: the ingredient's general function, its role in this product type, and what its position can support.

  • 1 Water · AQUA/WATER/EAU
    General function

    The base of almost every rinse-off and cream hair product. It carries everything else and is normally the first ingredient on the label.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    • solvent
  • 2 Cocamidopropyl Betaine
    General function

    A mild coconut-derived co-cleanser that boosts foam and softens the effect of stronger detergents. It appears in most shampoos, gentle or not.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    May suitDry, coarse, or high-porosity hair

    Mild cleansing leaves more surface lubrication in place on hair that dries out quickly.

    May not suitBuild-up-sensitive routines

    The mildest detergents are also the least complete: a routine that deposits films needs something stronger periodically.

    DependsVery dry or highly damaged hair

    Among the mildest detergents in use — it is what baby shampoos are built on — but it is almost always the second detergent in a formula. How much a wash strips is still decided by the primary detergent listed above it.

    Indian Journal of Dermatology
    • amphoteric cleanser
    • secondary cleanser
    • cleanser
  • 3 Sodium Methyl Oleoyl Taurate
    General function

    A mild cleanser that keeps foaming in hard water.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    May suitCurls or waves needing flexible hold

    The detergent class most curl routines are built around: it lathers and cleanses without stripping the strand back to bare.

    May suitDry, coarse, or high-porosity hair

    A gentler detergent leaves more of the surface oil that slows water loss from coarse or porous hair.

    May suitVery dry or highly damaged hair

    Cleanses with less sebum removal than a sulfate detergent, so hair that is short of moisture keeps more of it through the wash.

    PubChem
    • mild anionic cleanser
    • cleanser
  • 4 Sodium Lauroyl Sarcosinate
    General function

    A gentle cleanser that leaves a soft after-feel; often paired with stronger detergents.

    Supporting ingredient

    Listed in positions 4–8, it likely makes a meaningful contribution alongside the formula's main ingredients.

    May suitCurls or waves needing flexible hold

    The detergent class most curl routines are built around: it lathers and cleanses without stripping the strand back to bare.

    May suitDry, coarse, or high-porosity hair

    A gentler detergent leaves more of the surface oil that slows water loss from coarse or porous hair.

    May suitVery dry or highly damaged hair

    Cleanses with less sebum removal than a sulfate detergent, so hair that is short of moisture keeps more of it through the wash.

    PubChem
    • mild anionic cleanser
    • cleanser
  • Below about this point, order stops being meaningful — these are typically used at 1% or less.
  • 5 Fragrance · PARFUM/FRAGRANCE
    General function

    An undisclosed blend of scent ingredients. Regulations let it stay unlisted, so a fragrance-free product is the only way to be certain what is not in it.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May not suitFragrance-sensitive routines

    Declared fragrance. On a fragrance-sensitive routine this is the line that decides it, wherever it sits on the label.

    • fragrance
    • declared fragrance
  • 6 Phenoxyethanol
    General function

    The most common modern preservative; it keeps the product free of bacteria and mould. It sits well below 1% of the formula.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    PubChem
    • preservative
  • 7 Sodium Benzoate
    General function

    A food-grade preservative that works only in acidic formulas, which is why it usually appears alongside citric acid.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    PubChem
    • preservative
  • 8 Citric Acid
    General function

    Used to bring the product to a slightly acidic pH, which helps the cuticle lie flat. It is almost always near the end of the list.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitBuild-up-sensitive routines

    Holds hard-water minerals in solution so they rinse away instead of depositing on the hair.

    May suitFrizz-prone, damaged, or high-friction hair

    The acid side of pH adjustment, and the reason it matters is measured: alkaline formulas raise the fibre's surface negative charge, increase friction between strands and lift the scales, while lower-pH ones do the reverse.

    May suitGray, silver, or brass-prone hair

    Where a warm cast comes from water minerals rather than from the hair itself, holding those metals in solution is what removes it.

    International Journal of Trichology
    • pH adjuster
    • hard-water chelator
  • 9 Polyquaternium-10
    General function

    A cellulose-based conditioning polymer that leaves a thin, static-reducing film. Very common in shampoos as the ingredient that keeps them from stripping.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitCurls or waves needing flexible hold

    Cationic polymers hold a curl loosely and stay soft, which is why they turn up in definition products rather than firm-hold ones.

    May suitFrizz-prone, damaged, or high-friction hair

    A cationic polymer stays on the hair through rinsing, which is what keeps static and combing friction down after the wash.

    May suitMaximum-hold styling

    Film formers are what hold a style: they dry into a connected film across the strands so the shape resists movement.

    • conditioning agent
    • film former
    • polymer
  • 10 Glycerin
    General function

    A small water-loving molecule that draws moisture into the hair and holds it there. It is the most common softening ingredient in conditioners and leave-ins.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitDry, coarse, or high-porosity hair

    High-porosity hair loses water fast; a humectant holds some of it in place for longer than the wash itself would.

    May suitVery dry or highly damaged hair

    Binds water into the outer layers of the strand, and water is what makes dry hair flexible again rather than brittle.

    DependsClimate-sensitive or frizz-prone hair

    Water moves both ways. Measured across concentrations, glycerin solutions give water up in some conditions and take it from the air in others. What it does for you depends on how much of it is there and on the air around it.

    Scientific Reports
    • humectant
  • 11 Ethylhexylglycerin
    General function

    A preservative booster that also adds a little softness. Almost always paired with phenoxyethanol.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitFrizz-prone, damaged, or high-friction hair

    Emollients fill and smooth the surface of the strand, which lowers the friction that lifts the cuticle and reads as roughness.

    PubChem
    • preservative
    • emollient
  • 12 Aloe Barbadensis Leaf Juice
    General function

    Aloe gel, used for light moisture and slip. High in the list it also contributes a little natural hold.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitCurls or waves needing flexible hold

    Gums thicken and set soft, which gives definition that bends rather than a rigid cast.

    May suitFine or easily flattened hair

    Hydration with no oil attached, so it adds very little weight even high on a list.

    May suitVery dry or highly damaged hair

    Aloe is mostly water carrying sugars that bind more of it, which is why it turns up as the base of moisture-first formulas.

    • humectant
    • botanical extract
    • gum
  • 13 Isostearyl Alcohol
    General function

    A fatty ester. Esters give slip and a smooth after-feel; lighter ones read dry and silky, heavier ones read rich.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitFine or easily flattened hair

    A light emollient: it softens the surface with noticeably less weight than an oil or a butter.

    May suitFrizz-prone, damaged, or high-friction hair

    Spreads thin and lowers friction between strands without the heaviness of a fixed oil.

    PubChem
    • light ester
    • emollient
  • 14 BOSWELLIA SERRATA GUM
  • 15 Tocopherol
    • antioxidant
    • vitamin
  • 16 Potassium Sorbate
    • preservative
  • 17 Sodium Citrate
    General function

    Used with citric acid to hold the formula at a steady, slightly acidic pH. It also binds a little hard-water mineral.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitBuild-up-sensitive routines

    Binds the calcium and magnesium in hard water, which is what stops mineral deposits accumulating on the strand wash after wash.

    May suitGray, silver, or brass-prone hair

    Copper and iron carried in tap water deposit on the strand and read as a dull, warm cast on gray or light hair. A chelator holds those metals in solution so the wash carries them off.

    DependsFrizz-prone, damaged, or high-friction hair

    pH adjusters are how a formula is brought to a chosen acidity, and an acidic formula keeps the cuticle lying flatter than an alkaline one. Which way this one moves the pH depends on the formula, and the finished pH is not on the label.

    PubChem
    • pH adjuster
    • hard-water chelator
  • 18 Sodium Sulfite
    • antioxidant
    • preservative

What the whole list adds up to

  • 5 preservatives
  • 3 cleansers
  • 2 mild anionic cleansers
  • 2 pH adjusters
  • 2 hard-water chelators
  • 2 humectants
  • 2 emollients
  • 2 antioxidants
  • 1 solvent
  • 1 amphoteric cleanser
  • 1 secondary cleanser
  • 1 fragrance
  • 1 declared fragrance
  • 1 conditioning agent

Ingredient list captured 2026-09-11. Formulas change — check the package in your hand when an ingredient matters to you.

Price · 6.76 oz

Commonly seen about $27 Midpoint $27 · 5 stores · checked Sep 13
Good value under $6 Under $0.94/oz it costs less than three-quarters of the 8 products we score as doing the same job

Priced above the products that do the same job. Stores sell it above the $6 line; products that do this job typically go for about $13 at this size.

Sizes

6.76 ozmost listed
$27
$3.99/oz
33.8 oz
$63
$1.86/oz

The 33.8 oz costs 53% less per ounce than the 6.76 oz.

Show the price ladder
Where we’ve seen it7 listings · 6 stores

6.76 ozmost listed

33.8 ozBest per ounce

  • Amazon
    $63.00
    33.8 oz · $1.86/oz
    Sep 13Lowest per oz

Sorted by price per ounce. Dated observations from our research, not live prices. Direct store pages, no affiliate links. We don’t sell this product. and 1 listing we don’t count — grey-market or unverified sellers.

How we work this out
  1. 6.76 oz is the size stores list most often; every comparison on this page is made at it. Other sizes are shown in the Sizes row and the store list.
  2. Commonly seen is the middle half of current prices for the 6.76 oz at recognised stores — the cheapest quarter and the dearest quarter are left out, so one sale or one overpriced listing can’t move it.
  3. Good value under $6 comes from the 8 products we score as doing the same job as this one. A quarter of them cost less than $0.94/oz; at 6.76 oz that is $6. Under that line you are paying less than most of them.
  4. Each size is guarded on its own, so a multipack or a marketplace listing at one size cannot move another.
  5. About $13 is what those same products typically cost at this size — the midpoint of their prices per ounce, scaled to 6.76 oz.

Formula

Formula score
9 of 10

Sold through salons at a price 7 products that do the same job undercut — the distribution is part of what you are paying for.

How the score is counted
  • 7 products that do the same job cost less per ounce
  • Costs more per ounce than 85% of the 817 shampoos we’ve priced
  • Covers 6 of the 7 things a shampoo should do
  • Salon tier, sold at Brand website and Salons
  • A working detergent systemWhat actually removes oil and product.3 pts
  • Slip for detanglingReduces the force it takes to comb wet hair.2 pts
  • A humectantBinds water into the hair.1 pt
  • A hard-water chelatorBinds the minerals that dull hair in hard water.1 pt
  • A pH adjusterBrings the formula to the acidic pH hair prefers.1 pt
  • No detergent-dependent filmNothing that needs a clarifying wash to remove.1 pt
  • Fragrance kept out of the top eightScent as a finishing touch, not a major share.1 pt

The formula score is completeness for the job: the share of the systems this product type is normally built around that we can find in this list, weighted. It is not efficacy, not quality, and it never compares across product types.

Does the same job, for less

Same derived functions — what it cleans, conditions, coats or holds — at a lower cost per ounce. Scent, texture and where you buy it can still differ.

TRESemmeLowest cost per oz Pro Pure Curl Define Shampoo $0.36/oz $3.63/oz less
  • Sulfate-free
  • Protein-free
  • Curly method
· Close function
Function
  • Hard-water defence
Also
  • Cruelty-free
  • Drugstore tier
Compare
TRESemmeClose function Pro Pure Damage Recovery Shampoo $2.05/oz $1.94/oz less
  • Sulfate-free
  • Protein-free
  • Curly method
Function
  • Hard-water defence
Also
  • Cruelty-free
  • Drugstore tier
Compare
Carol's DaughterClose function Black Vanilla Moisture & Shine Sulfate Free Shampoo $1.05/oz $2.94/oz less
  • Sulfate-free
  • Protein-free
  • Curly method
Function
  • Slip and detangling
Also
  • Sweet scent
  • Cruelty-free
  • Drugstore tier
Compare

See more alternatives in the product library

These are functional neighbours, not personal recommendations — they are close on formula, not chosen for anyone. Get the one that fits your hair, routine, and budget

Suits every hair pattern

Final decision

Should you buy it?

Good for the right person, not the lowest cost
Best user

Colour-treated hair who want washing without sulfates and a protein-free formula

Biggest tradeoff

Not ideal for anyone sensitive to fragrance, soft, over-stretchy hair that needs protein, or hard water without a chelating wash

We do not sell products or take placement fees. This page states what the formula and the prices show; the consultation is what matches it to a person.

Claims check

What the brand says, against what the formula shows

Claims are quoted from the brand. We only mark one supported, partly supported, or conflicting when the ingredient list actually speaks to it; everything else stays "stated by the brand", which is not a criticism — most claims simply cannot be read off a label.

0
SupportedBacked by ingredients
0
Partly supportedSome supporting logic
1
Stated by brandNo clear evidence
0
Potential conflictFormula works against claim
SENSITIVE, DRY & ITCHY SCALP

No over-the-counter anti-dandruff active appears in the list.

Stated by brand

Soothing, not an active treatment.

How to read this

We look at the first 10–15 ingredients and what they do in a formula — not marketing. If the list doesn't speak to a claim, we don't assume.

More from Nioxin

How this page was made

  • Everything above is generated from our researched product record — identity, the ingredient list as printed, the brand's own claims, dated price observations, and review themes written in our researchers' own words. No part of this page is written per product.
  • The value band is a fixed label over two stored numbers: this product’s cost per ounce as a percentile of every product of this type we have priced, each at the size it is most often sold in, and how many products we score as doing the same job cost at least a quarter less per ounce.
  • Both scores out of ten are defined on this page. The formula score is completeness for the job, computed from a fixed per-format checklist shown beneath the gauge; the price score is cost per ounce against every product of this type we have priced.
  • The "Is this right for you?" panel reads only your own consultation answers, and it applies exactly the filters our recommendation engine applies. It is computed when you load the page and is never stored on it.
  • 6 sources consulted for this product (0 manufacturer or regulatory, 3 retailer, 3 editorial), last checked 2026-09-13.
  • Ingredient references are linked for 8 of 11 product-aware annotations on this page. Fit notes are conditional formulation guidance, not a conclusion about the finished product or about you.
  • We have not tested this product in a lab and we do not physically test your hair. Formula readings come from the ingredient list; behaviour claims are labelled as the brand's.
  • Ingredient order tells you relative amount only above roughly 1%. Prices are observations on the dates shown and change without notice.
  • Ingredient names link to our ingredient library, where each entry shows what it does, which product types use it, and where it usually sits on a label across everything we have researched.
  • This is cosmetic information, not medical advice, and nothing here diagnoses or treats a health condition.
  • Formula readings: derivation v22. Record last updated 2026-09-11.