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Nioxin

Pro Clinical Scalp Relief Cleansing Shampoo

Shampoo / Everyday cleanser, balanced

  • Shampoo
  • Sulfate-free
  • Silicone-free
  • Protein-free
  • Not cruelty-free · PETA-listed
Size6.76 fl oz (200 ml)usual store size · 2 sizes
Priceabout $27commonly seen · 6.76 oz · from $1.86/oz in the 33.8 oz
Price / oz$3.99/ozat 6.76 oz
Where to buy6 stores · 2 sizes

Add it to your products. We’ll tell you if it’s ever recalled.

Scent:

The ingredient list declares fragrance. What it smells of is not stated, and we do not guess.

Manufacturer page: nioxin.com

Personal fit

Is this right for you?

Complete the consultation to see how well this product fits your hair and your goals. With 6,000+ products in our library, we can match you to the right ones.

  • About 20 minutes, and your answers save as you go.
  • Every product matched against your hair across the 22 factors we check.
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  • Find products that do the same job at a lower cost.
  • Your goals, scalp, damage history, water, budget, and scent preferences all shape your plan.

$49 with 60 days of follow-up questions and plan updates

$99 with 12 months. Pay once; the year renews only if you choose.

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Same job for less elsewhere

$3.99/oz at 6.76 oz, more than 84% of the 1544 shampoos , which mostly run $0.79–3.04/oz.

View alternatives

Great for

Colour-treated hairthat fades faster in a sulfate wash
Protein-sensitive hairthat stiffens when protein is added
Curly-method routinesno sulfates and no water-insoluble silicones
Fine hairthat flattens under most products
Silicone-free routinesno silicones appear in the list
Very dry hairno fast-drying alcohol in the list

Maybe skip if

this product has a scent
Hair that needs proteinthere is none in this list
Hard waterno chelator here to bind the minerals
Vegan and cruelty-freeour record does not support both claims here
Tight budgetsit sits in the upper price tiers

How much cleansing you need depends on how fast your scalp gets oily, how much product you layer and your water. The consultation works that out.

What the formula actually does

Read from the label, not the marketing

Each row says where it comes from: F means we derived it from this product’s own ingredient list, S means it is a claim the brand makes that the formula neither confirms nor contradicts.

Cleansing strength Moderate

Removes oil and product; leaves some conditioning behind.

Expected lather Moderate

An ordinary shampoo lather.

Slip and detangling Moderate

Conditioning agents are present, lower in the list.

Water-binding (humectants) Moderate

Humectants in the working part of the formula.

Scalp active None

No over-the-counter scalp active.

Hard-water defence None

No chelating agent in the list.

Needs detergent to remove No

Nothing here needs a detergent wash to remove.

Protein None

No protein or amino acids in the list.

Fragrance Prominent

Fragrance is in the first eight ingredients, so it makes up a larger share of the formula.

from the formula stated by the brand reported by reviewers Scale: 1 dot low · 5 dots high, within this product type.

Ingredients that matter

The ingredients that change a decision

The workhorse ingredients, plus anything lower down that changes a decision. The chips name what an ingredient does. They are not safety scores, and no ingredient here is rated good or bad on its own.

IngredientWhat it doesWhy it mattersChip
WaterAQUA/WATER/EAU solvent The base everything else is dissolved in Neutral
Cocamidopropyl Betaine amphoteric cleanser — Cleanses
Sodium Methyl Oleoyl Taurate mild anionic cleanser — Cleanses
Sodium Lauroyl Sarcosinate mild anionic cleanser — Cleanses
FragrancePARFUM/FRAGRANCE fragrance The scent Fragrance
Phenoxyethanol preservative Keeps the product from spoiling Stabilizes
Sodium Benzoate preservative Keeps the product from spoiling Stabilizes
Citric Acid pH adjuster Fine-tunes the pH pH balancer
What the list leaves out, and what it carriesThe list carries no sulfates, silicones, or drying alcohols. No protein: a moisture formula, not a repair one. Fragrance is on the label.
Full ingredient list (18)

In the US, ingredients above 1% are listed from most to least. Below 1% they can appear in any order. Each note keeps three things apart: what the ingredient generally does, its role in this type of product, and what its position can tell you.

  • 1 Water · AQUA/WATER/EAU
    General function

    The base of almost every rinse-off and cream hair product. It carries everything else and is normally the first ingredient on the label.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    • solvent
  • 2 Cocamidopropyl Betaine
    General function

    A mild coconut-derived co-cleanser that boosts foam and softens the effect of stronger detergents. It appears in most shampoos, gentle or not.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    May suitDry, coarse, or high-porosity hair

    Mild cleansing leaves more surface lubrication in place on hair that dries out quickly.

    May not suitBuild-up-sensitive routines

    The mildest detergents are also the least complete: a routine that deposits films needs something stronger periodically.

    DependsVery dry or highly damaged hair

    Among the mildest detergents in use — it is what baby shampoos are built on — but it is almost always the second detergent in a formula. How much a wash strips is still decided by the primary detergent listed above it.

    Indian Journal of Dermatology
    • amphoteric cleanser
    • secondary cleanser
    • cleanser
  • 3 Sodium Methyl Oleoyl Taurate
    General function

    A mild cleanser that keeps foaming in hard water.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    May suitCurls or waves needing flexible hold

    The detergent class most curl routines are built around: it lathers and cleanses without stripping the strand back to bare.

    May suitDry, coarse, or high-porosity hair

    A gentler detergent leaves more of the surface oil that slows water loss from coarse or porous hair.

    May suitVery dry or highly damaged hair

    Cleanses with less sebum removal than a sulfate detergent, so hair that is short of moisture keeps more of it through the wash.

    PubChem
    • mild anionic cleanser
    • cleanser
  • 4 Sodium Lauroyl Sarcosinate
    General function

    A gentle cleanser that leaves a soft after-feel; often paired with stronger detergents.

    Supporting ingredient

    Listed in positions 4–8, it likely makes a meaningful contribution alongside the formula's main ingredients.

    May suitCurls or waves needing flexible hold

    The detergent class most curl routines are built around: it lathers and cleanses without stripping the strand back to bare.

    May suitDry, coarse, or high-porosity hair

    A gentler detergent leaves more of the surface oil that slows water loss from coarse or porous hair.

    May suitVery dry or highly damaged hair

    Cleanses with less sebum removal than a sulfate detergent, so hair that is short of moisture keeps more of it through the wash.

    PubChem
    • mild anionic cleanser
    • cleanser
  • ▾Below about here, the order stops meaning much. These are usually used at 1% or less.
  • 5 Fragrance · PARFUM/FRAGRANCE
    General function

    An undisclosed blend of scent ingredients. Regulations let it stay unlisted, so a fragrance-free product is the only way to be certain what is not in it.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May not suitFragrance-sensitive routines

    Declared fragrance. On a fragrance-sensitive routine this is the line that decides it, wherever it sits on the label.

    • fragrance
    • declared fragrance
  • 6 Phenoxyethanol
    General function

    The most common modern preservative; it keeps the product free of bacteria and mould. It sits well below 1% of the formula.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    PubChem
    • preservative
  • 7 Sodium Benzoate
    General function

    A food-grade preservative that works only in acidic formulas, which is why it usually appears alongside citric acid.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    PubChem
    • preservative
  • 8 Citric Acid
    General function

    Used to bring the product to a slightly acidic pH, which helps the cuticle lie flat. It is almost always near the end of the list.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitBuild-up-sensitive routines

    Holds hard-water minerals in solution so they rinse away instead of depositing on the hair.

    May suitFrizz-prone, damaged, or high-friction hair

    The acid side of pH adjustment, and the reason it matters is measured: alkaline formulas raise the fibre's surface negative charge, increase friction between strands and lift the scales, while lower-pH ones do the reverse.

    May suitGray, silver, or brass-prone hair

    Where a warm cast comes from water minerals rather than from the hair itself, holding those metals in solution is what removes it.

    International Journal of Trichology
    • pH adjuster
    • hard-water chelator
  • 9 Polyquaternium-10
    General function

    A cellulose-based conditioning polymer that leaves a thin, static-reducing film. Very common in shampoos as the ingredient that keeps them from stripping.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitCurls or waves needing flexible hold

    Cationic polymers hold a curl loosely and stay soft, which is why they turn up in definition products rather than firm-hold ones.

    May suitFrizz-prone, damaged, or high-friction hair

    A cationic polymer stays on the hair through rinsing, which is what keeps static and combing friction down after the wash.

    May suitMaximum-hold styling

    Film formers are what hold a style: they dry into a connected film across the strands so the shape resists movement.

    • conditioning agent
    • film former
    • polymer
  • 10 Glycerin
    General function

    Glycerin, also called glycerol, attracts moisture and mixes completely with water.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitDry, coarse, or high-porosity hair

    High-porosity hair loses water fast; a humectant holds some of it in place for longer than the wash itself would.

    May suitVery dry or highly damaged hair

    Binds water into the outer layers of the strand, and water is what makes dry hair flexible again rather than brittle.

    DependsClimate-sensitive or frizz-prone hair

    Water moves both ways. Measured across concentrations, glycerin solutions give water up in some conditions and take it from the air in others. What it does for you depends on how much of it is there and on the air around it.

    Scientific Reports
    • humectant
  • 11 Ethylhexylglycerin
    General function

    A preservative booster that also adds a little softness. Almost always paired with phenoxyethanol.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitFrizz-prone, damaged, or high-friction hair

    Emollients fill and smooth the surface of the strand, which lowers the friction that lifts the cuticle and reads as roughness.

    PubChem
    • preservative
    • emollient
  • 12 Aloe Barbadensis Leaf Juice
    General function

    Aloe gel, used for light moisture and slip. High in the list it also contributes a little natural hold.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitCurls or waves needing flexible hold

    Gums thicken and set soft, which gives definition that bends rather than a rigid cast.

    May suitFine or easily flattened hair

    Hydration with no oil attached, so it adds very little weight even high on a list.

    May suitVery dry or highly damaged hair

    Aloe is mostly water carrying sugars that bind more of it, which is why it turns up as the base of moisture-first formulas.

    • humectant
    • botanical extract
    • gum
  • 13 Isostearyl Alcohol
    General function

    A fatty ester. Esters give slip and a smooth after-feel; lighter ones read dry and silky, heavier ones read rich.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitFine or easily flattened hair

    A light emollient: it softens the surface with noticeably less weight than an oil or a butter.

    May suitFrizz-prone, damaged, or high-friction hair

    Spreads thin and lowers friction between strands without the heaviness of a fixed oil.

    PubChem
    • light ester
    • emollient
  • 14 BOSWELLIA SERRATA GUM
  • 15 Tocopherol
    • antioxidant
    • vitamin
  • 16 Potassium Sorbate
    • preservative
  • 17 Sodium Citrate
    General function

    Used with citric acid to hold the formula at a steady, slightly acidic pH. It also binds a little hard-water mineral.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitBuild-up-sensitive routines

    Binds the calcium and magnesium in hard water, which is what stops mineral deposits accumulating on the strand wash after wash.

    May suitGray, silver, or brass-prone hair

    Copper and iron carried in tap water deposit on the strand and read as a dull, warm cast on gray or light hair. A chelator holds those metals in solution so the wash carries them off.

    DependsFrizz-prone, damaged, or high-friction hair

    pH adjusters are how a formula is brought to a chosen acidity, and an acidic formula keeps the cuticle lying flatter than an alkaline one. Which way this one moves the pH depends on the formula, and the finished pH is not on the label.

    PubChem
    • pH adjuster
    • hard-water chelator
  • 18 Sodium Sulfite
    • antioxidant
    • preservative

What the whole list adds up to

  • 5 preservatives
  • 3 cleansers
  • 2 mild anionic cleansers
  • 2 pH adjusters
  • 2 hard-water chelators
  • 2 humectants
  • 2 emollients
  • 2 antioxidants
  • 1 solvent
  • 1 amphoteric cleanser
  • 1 secondary cleanser
  • 1 fragrance
  • 1 declared fragrance
  • 1 conditioning agent

Ingredient list captured 2026-09-11. Formulas change, so check the package in your hand when an ingredient matters to you.

Price · 6.76 oz

Commonly seen about $27 Midpoint $27 · 5 stores · checked Sep 13
Good value under $5 Under $0.79/oz it costs less than three-quarters of the 8 products we score as doing the same job

Priced above the products that do the same job. Stores sell it above the $5 line; products that do this job typically go for about $12 at this size.

Sizes

6.76 ozusual store size
$27
$3.99/oz
33.8 oz
$63
$1.86/oz

The 33.8 oz costs 53% less per ounce than the 6.76 oz.

Show the price ladder
Where we’ve seen it7 listings · 6 stores

6.76 ozusual store size

33.8 ozBest per ounce

  • Amazon
    $63.00
    33.8 oz · $1.86/oz
    Sep 13Lowest per oz

Sorted by price per ounce. Dated observations from our research, not live prices. Direct store pages, no affiliate links. We don’t sell this product. and 1 listing we don’t count, from grey-market or unverified sellers.

How we work this out
  1. 6.76 oz is the size stores list most often; every comparison on this page is made at it. Other sizes are shown in the Sizes row and the store list.
  2. Commonly seen is the middle half of current prices for the 6.76 oz at recognised stores. We leave out the cheapest and most expensive quarters, so one sale or one overpriced listing can’t move it.
  3. Good value under $5 comes from the 8 products we score as doing the same job as this one. A quarter of them cost less than $0.79/oz; at 6.76 oz that is $5. Under that line you are paying less than most of them.
  4. Each size is guarded on its own, so a multipack or a marketplace listing at one size cannot move another.
  5. About $12 is what those same products typically cost at this size: the midpoint of their prices per ounce, scaled to 6.76 oz.

Formula

Formula score
9 of 10

Sold through salons, and 7 products that do the same job cost less. Part of what you pay for is where it is sold.

How the score is counted
  • 7 products that do the same job cost less per ounce
  • Costs more per ounce than 84% of the 1544 shampoos we’ve priced
  • Covers 6 of the 7 things a shampoo should do
  • Salon tier, sold at Brand website and Salons
  • A working detergent systemWhat actually removes oil and product.3 pts
  • Slip for detanglingReduces the force it takes to comb wet hair.2 pts
  • A humectantBinds water into the hair.1 pt
  • A hard-water chelatorBinds the minerals that dull hair in hard water.1 pt
  • A pH adjusterBrings the formula to the acidic pH hair prefers.1 pt
  • No detergent-dependent filmNothing that needs a clarifying wash to remove.1 pt
  • Fragrance kept out of the top eightScent as a finishing touch, not a major share.1 pt

The formula score measures completeness for the job: a weighted share of the systems this product type is usually built around that we find in this list. It does not rate how well the product works or its quality, and it never compares across product types.

Does the same job, for less

Formulas that do the same things (cleanse, condition, coat or hold) for less per ounce. Scent, texture and where you buy them can still differ.

DoveLowest cost per oz Men Care Hydration 2 In 1 Shampoo $0.57/oz $3.42/oz less
  • Sulfate-free
  • Protein-free
  • Curly method
· Same function
Differs
  • Coconut scent
  • Cruelty-free
  • Vegan
Compare
PhytoClose function PLAGE After Sun Rehydrating Shampoo $2.62/oz $1.37/oz less
  • Sulfate-free
  • Protein-free
  • Curly method
Function
  • Slip and detangling
Also
  • 8.4 oz bottle
  • Sold at specialty beauty counters
Compare
PhytoClose function BLONDE Brightening Shampoo $2.62/oz $1.37/oz less
  • Sulfate-free
  • Protein-free
  • Curly method
Function
  • Slip and detangling
Also
  • 8.4 oz bottle
  • Sold at specialty beauty counters
Compare

See more alternatives in the product library

These products do a similar job. We haven’t matched them to you. Find the one that fits your hair, routine and budget

Suits every hair pattern

Final decision

Should you buy it?

Good for the right person, not the lowest cost
Best user

Colour-treated hair who want washing without sulfates and a protein-free formula

Biggest tradeoff

Not ideal for anyone sensitive to fragrance, soft, over-stretchy hair that needs protein, or hard water without a chelating wash

We do not sell products or take placement fees. This page states what the formula and the prices show; the consultation is what matches it to a person.

Claims check

What the brand says, and what the formula shows

Claims are quoted from the brand. We mark a claim supported, partly supported or conflicting only when the ingredient list speaks to it. Everything else stays "stated by the brand". That isn’t a criticism: most claims can’t be checked from a label.

0
SupportedBacked by ingredients
0
Partly supportedSome supporting logic
1
Stated by brandNo clear evidence
0
Potential conflictFormula works against claim
SENSITIVE, DRY & ITCHY SCALP

No over-the-counter anti-dandruff active appears in the list.

—

Stated by brand

Soothing, not an active treatment.

How to read this

We look at the first 10–15 ingredients and what they do in a formula, not at the marketing. If the list doesn't speak to a claim, we don't assume.

More from Nioxin

How this page was made

  • Everything above comes from our researched product record: identity, the ingredient list as printed, the brand's own claims, dated prices and review themes our researchers wrote in their own words. No part of this page is written by hand for one product.
  • The value band is a fixed label over two stored numbers: this product’s cost per ounce as a percentile of every product of this type we have priced, each at the size it is most often sold in, and how many products we score as doing the same job cost at least a quarter less per ounce.
  • Both scores out of ten are defined on this page. The formula score is completeness for the job, computed from a fixed per-format checklist shown beneath the gauge; the price score is cost per ounce against every product of this type we have priced.
  • The "Is this right for you?" panel reads only your own consultation answers, and it applies exactly the filters our recommendation engine applies. It is computed when you load the page and is never stored on it.
  • 7 sources consulted for this product (0 manufacturer or regulatory, 4 retailer, 3 editorial), last checked 2026-10-31.
  • Ingredient references are linked for 8 of 11 product-aware annotations on this page. Fit notes are general formulation guidance. They aren’t a verdict on the finished product or on you.
  • We haven’t tested this product in a lab, and we don’t physically test your hair. Formula readings come from the ingredient list. Claims about how it behaves are labelled as the brand's.
  • Ingredient order tells you relative amount only above roughly 1%. Prices are what we saw on the dates shown and can change.
  • Ingredient names link to our ingredient library, where each entry shows what it does, which product types use it, and where it usually sits on a label across everything we have researched.
  • This is cosmetic information, not medical advice, and nothing here diagnoses or treats a health condition.
  • Formula readings: derivation v23. Record last updated 2026-10-03.

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