Lightweight and non-greasy
Light silicones and low wax content help it avoid visible residue.
- Alcohol Denat.
- Water
- Butylene Glycol
Supported
Less likely to weigh hair down.
Nioxin
Pro Clinical Night Density Rescue Serum
Scalp treatment
- Scalp treatment
- serum
- Sulfate-free
- Silicone-free
- Protein-free
- Not cruelty-free · PETA-listed
Size2.3 fl oz (70 ml)
Price$38–50commonly seen · 2.3 oz
Price / oz$21.10/ozat 2.3 oz
Where to buy4 stores · $25.00–50.00
Add it to your products. We’ll tell you if it’s ever recalled.
Scent:
The ingredient list declares fragrance. What it smells of is not stated, and we do not guess.
Manufacturer page: nioxin.com
Personal fit
Is this right for you?
Complete the consultation to see how well this product fits your hair and your goals. With 6,000+ products in our library, we can match you to the right ones.
- About 20 minutes, and your answers save as you go.
- Every product matched against your hair across the 19 factors we check.
- A personalized routine built around your schedule, styling habits, and local weather.
- Find products that do the same job at a lower cost.
- Your goals, scalp, damage history, water, budget, and scent preferences all shape your plan.
$49 with 60 days of follow-up questions and plan updates
$99 with 12 months. Pay once; the year renews only if you choose.
Factor
Your profile
Fit
Best for hair types
All types
Not in your profile
Moisture level
High
Not in your profile
Slip / detangling
Little
Not in your profile
Weight on hair
Light
Not in your profile
Fragrance
Prominent
Not in your profile
Protein
None
Not in your profile
Silicone / wax buildup
None
Not in your profile
Clarifying wash needed
Moderate
Not in your profile
Parabens / preservatives
None of these listed
Not in your profile
Essential oils
None listed
Not in your profile
Show all 19 factors we check
The rest of what your plan weighs on this product.
Fast-drying alcohol
High
Not in your profile
Vegan / cruelty-free
Not cruelty-free · PETA-listed
Not in your profile
Animal-derived ingredients
Not yet verified
Not in your profile
Heavy humectants
Not heavy
Not in your profile
Hard-water defence
None
Not in your profile
UV filter
None listed
Not in your profile
Ingredient list
25 ingredientsAbout average
Not in your profile
Price tier
Prestige
Not in your profile
Where to buy it
Salons · Specialty beauty +1Widely sold
Not in your profile
The consultation builds your hair profile, checks every factor in this table against it, and tells you where this product fits or what to use instead.
Start your consultation$49 once, with 60 days of follow-up questions and plan updates. Nothing renews, and you never have to buy a product.
Your avoid-list
Same job for less elsewhere
$21.10/oz at 2.3 oz, more than 79% of the 280 scalp treatments , which mostly run $3.84–19.05/oz.
Great for
Protein-sensitive hairthat stiffens when protein is added
Fine hairthat flattens under most products
Silicone-free routinesno silicones appear in the list
Easy to findsold through several channels
Maybe skip if
this product has a scent
Very dry or damaged hairit contains fast-drying alcohol
Vegan and cruelty-freeour record does not support both claims here
Tight budgetsit sits in the upper price tiers
What the formula actually does
Read from the label, not the marketing
Each row says where it comes from: F means we derived it from this product’s own ingredient list, S means it is a claim the brand makes that the formula neither confirms nor contradicts.
Slip and detangling
Little
Nothing here is built to reduce combing force.
Oils and butters
None
No oils or butters in the list.
Weight on the hair
Light
Water-first and light: unlikely to flatten fine hair.
Water-binding (humectants)
High
Humectants near the top: binding water is one of its main jobs.
Protein
None
No protein or amino acids in the list.
Needs detergent to remove
No
Nothing here needs a detergent wash to remove.
Hard-water defence
None
No chelating agent in the list.
Fragrance
Prominent
Fragrance is in the first eight ingredients, so it makes up a larger share of the formula.
from the formula
stated by the brand
reported by reviewers
Scale: 1 dot low · 5 dots high, within this product type.
Ingredients that matter
The ingredients that change a decision
The workhorse ingredients, plus anything lower down that changes a decision. The chips name what an ingredient does. They are not safety scores, and no ingredient here is rated good or bad on its own.
| Ingredient | What it does | Why it matters | Chip |
|---|---|---|---|
| Alcohol Denat.ALCOHOL DENAT | drying alcohol | Speeds drying but can leave hair feeling dry | Drying |
| WaterAQUA/WATER/EAU | solvent | The base everything else is dissolved in | Neutral |
| Caffeine | active | The over-the-counter active | Active |
| Panthenol | humectant | Pulls water into the hair | Detangles |
| FragrancePARFUM/FRAGRANCE | fragrance | The scent | Fragrance |
| Menthol | fragrance | The scent | Fragrance |
| Lauric Acid | emulsifier | Stabilises the mix | Stabilizes |
| PEG-40 Hydrogenated Castor Oil | solubilizer | Helps dissolve the oils | Stabilizes |
| Linalool | fragrance | The scent | Fragrance |
| Hexyl Cinnamal | fragrance | The scent | Fragrance |
| Limonene | fragrance | The scent | Fragrance |
| Citronellol | fragrance | The scent | Fragrance |
What the list leaves out, and what it carriesThe list carries no sulfates or silicones. No protein: a moisture formula, not a repair one. Fragrance is on the label. Contains fast-drying alcohol.
Full ingredient list (25)
In the US, ingredients above 1% are listed from most to least. Below 1% they can appear in any order. Each note keeps three things apart: what the ingredient generally does, its role in this type of product, and what its position can tell you.
-
1
Alcohol Denat.
· ALCOHOL DENAT
General function
Fast-drying alcohol used to make sprays set quickly. In leave-on products it can leave hair feeling dry, especially in high position on the list.
Leading ingredientListed in the first three ingredients, it is likely a structural part of this formula.
PubChemMay suitFine or easily flattened hairEvaporates on contact, which is how a spray sets almost instantly and leaves no weight behind it.
May not suitDry, coarse, or high-porosity hairPorous hair gives water up easily as it is; a fast-evaporating solvent high on the list accelerates that.
May not suitVery dry or highly damaged hairIt evaporates quickly and takes some water with it. On hair already short of moisture, a formula built on a lot of it can finish drier than it started.
- drying alcohol
- solvent
-
2
Water
· AQUA/WATER/EAU
General function
The base of almost every rinse-off and cream hair product. It carries everything else and is normally the first ingredient on the label.
Leading ingredientListed in the first three ingredients, it is likely a structural part of this formula.
- solvent
-
3
Caffeine
General function
Included in scalp and thickening products for label appeal. Evidence for applied caffeine changing hair growth is limited.
Leading ingredientPubChemListed in the first three ingredients, it is likely a structural part of this formula.
- active
-
4
Panthenol
General function
Provitamin B5. It draws in water and penetrates the strand a little, which is why it is the standard ingredient for softness and shine claims.
Supporting ingredientListed in positions 4–8, it likely makes a meaningful contribution alongside the formula's main ingredients.
PubChemMay suitFine or easily flattened hairIt hydrates without adding oil or a film, which is the combination fine hair usually needs.
May suitFrizz-prone, damaged, or high-friction hairDeposits a lubricating layer that makes combing easier, which is most of what stops mechanical damage adding to frizz.
May suitVery dry or highly damaged hairA humectant that also penetrates the cuticle, so it holds water inside the strand rather than only on the surface.
- humectant
- conditioning agent
- vitamin
- ▾Below about here, the order stops meaning much. These are usually used at 1% or less.
-
5
Fragrance
· PARFUM/FRAGRANCE
General function
An undisclosed blend of scent ingredients. Regulations let it stay unlisted, so a fragrance-free product is the only way to be certain what is not in it.
Estimated lower-concentration zoneIt appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.
May not suitFragrance-sensitive routinesDeclared fragrance. On a fragrance-sensitive routine this is the line that decides it, wherever it sits on the label.
- fragrance
- declared fragrance
-
6
Menthol
General function
Produces the cooling, tingling feeling on the scalp. The sensation is real; it is not evidence that anything else is happening.
Estimated lower-concentration zoneIt appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.
PubChemMay not suitFragrance-sensitive routinesDeclared fragrance. On a fragrance-sensitive routine this is the line that decides it, wherever it sits on the label.
- fragrance
- active
-
7
Lauric Acid
General function
A coconut-derived fatty acid used to build cleansers and stabilise foam.
Estimated lower-concentration zonePubChemIt appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.
- emulsifier
-
8
PEG-40 Hydrogenated Castor Oil
General function
A castor-oil derivative that dissolves fragrance and oils into water so the product stays clear and does not separate.
Estimated lower-concentration zoneIt appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.
- solubilizer
- emulsifier
-
9
Tocopheryl Acetate
- antioxidant
- vitamin
- 10 PEG-35 CASTOR OIL
-
11
Butylene Glycol
General function
A light humectant and carrier that helps extracts dissolve.
Estimated lower-concentration zoneIt appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.
PubChemMay suitFine or easily flattened hairLight and water-binding rather than oily, so it adds less weight than oils or butters do.
May suitVery dry or highly damaged hairA small water-binding solvent. It holds moisture and helps the rest of the formula spread evenly over the strand.
DependsClimate-sensitive or frizz-prone hairA humectant follows the air: it holds water in humid conditions and can give it up in very dry ones. Climate decides what it does more than the label does.
- humectant
- solvent
-
12
Propylene Glycol
General function
A small humectant and solvent that keeps formulas stable and helps active ingredients spread.
Estimated lower-concentration zoneIt appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.
PubChemMay suitFine or easily flattened hairLight and water-binding rather than oily, so it adds less weight than oils or butters do.
May suitVery dry or highly damaged hairA small water-binding solvent. It holds moisture and helps the rest of the formula spread evenly over the strand.
DependsClimate-sensitive or frizz-prone hairA humectant follows the air: it holds water in humid conditions and can give it up in very dry ones. Climate decides what it does more than the label does.
- humectant
- solvent
-
13
Linalool
General function
A floral fragrance component listed separately as a recognised contact allergen.
Estimated lower-concentration zoneIt appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.
PubChemMay not suitFragrance-sensitive routinesOne of the 26 scent components the EU requires to be named individually above a threshold. It is named because it is a known contact allergen, not because it is unusual.
- fragrance
- named fragrance allergen
-
14
Polysorbate 20
- solubilizer
- emulsifier
-
15
Zingiber Officinale (Ginger) Root Extract
- botanical extract
-
16
Hexyl Cinnamal
General function
A jasmine-like fragrance component named separately as a recognised allergen.
Estimated lower-concentration zoneIt appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.
PubChemMay not suitFragrance-sensitive routinesOne of the 26 scent components the EU requires to be named individually above a threshold. It is named because it is a known contact allergen, not because it is unusual.
- fragrance
- named fragrance allergen
-
17
Limonene
General function
A citrus-smelling fragrance component that EU rules require to be named separately because some people react to it.
Estimated lower-concentration zoneIt appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.
PubChemMay not suitFragrance-sensitive routinesOne of the 26 scent components the EU requires to be named individually above a threshold. It is named because it is a known contact allergen, not because it is unusual.
- fragrance
- named fragrance allergen
-
18
Citronellol
General function
A rose-like fragrance component named separately as a recognised allergen.
Estimated lower-concentration zoneIt appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.
PubChemMay not suitFragrance-sensitive routinesOne of the 26 scent components the EU requires to be named individually above a threshold. It is named because it is a known contact allergen, not because it is unusual.
- fragrance
- named fragrance allergen
-
19
Passiflora Edulis Fruit Extract
- botanical extract
-
20
Geraniol
General function
A rose-scented fragrance component, listed on its own because some people react to it.
Estimated lower-concentration zoneIt appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.
May not suitFragrance-sensitive routinesOne of the 26 scent components the EU requires to be named individually above a threshold. It is named because it is a known contact allergen, not because it is unusual.
- fragrance
- named fragrance allergen
-
21
Potassium Sorbate
- preservative
-
22
Sodium Benzoate
- preservative
-
23
Citral
General function
A lemon-scented fragrance component listed separately as a recognised allergen.
Estimated lower-concentration zoneIt appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.
PubChemMay not suitFragrance-sensitive routinesOne of the 26 scent components the EU requires to be named individually above a threshold. It is named because it is a known contact allergen, not because it is unusual.
- fragrance
- named fragrance allergen
-
24
Sorbic Acid
- preservative
-
25
Farnesol
General function
A soft floral fragrance component listed separately as a recognised allergen.
Estimated lower-concentration zoneIt appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.
May not suitFragrance-sensitive routinesOne of the 26 scent components the EU requires to be named individually above a threshold. It is named because it is a known contact allergen, not because it is unusual.
- fragrance
- named fragrance allergen
What the whole list adds up to
- 9 fragrances
- 7 named fragrance allergens
- 4 solvents
- 3 humectants
- 3 emulsifiers
- 3 preservatives
- 2 actives
- 2 vitamins
- 2 solubilizers
- 2 botanical extracts
- 1 drying alcohol
- 1 conditioning agent
- 1 declared fragrance
- 1 antioxidant
Ingredient list captured 2026-09-11. Formulas change, so check the package in your hand when an ingredient matters to you.
Price · 2.3 oz
Commonly seen
$38–50
Good value under
$8
Priced above the products that do the same job. Stores sell it above the $8 line; products that do this job typically go for about $15 at this size.
Show the price ladder
Where we’ve seen it3 listings · 3 stores
-
United Salon Supplies
$25.002.3 oz · $10.87/ozSep 11Lowest per ozSale · was $50.00
-
Amazon
$50.002.37 oz · $21.10/ozSep 13
-
Ulta Beauty
$50.002.3 oz · $21.74/ozSep 11
Sorted by price per ounce. Dated observations from our research, not live prices. Direct store pages, no affiliate links. We don’t sell this product. and 1 listing we don’t count, from grey-market or unverified sellers.
How we work this out
- 2.3 oz is the size stores list most often; every comparison on this page is made at it. Other sizes are shown in the Sizes row and the store list.
- Commonly seen is the middle half of current prices for the 2.3 oz at recognised stores. We leave out the cheapest and most expensive quarters, so one sale or one overpriced listing can’t move it.
- Good value under $8 comes from the 8 products we score as doing the same job as this one. A quarter of them cost less than $3.46/oz; at 2.3 oz that is $8. Under that line you are paying less than most of them.
- About $15 is what those same products typically cost at this size: the midpoint of their prices per ounce, scaled to 2.3 oz.
Formula
1
Formula score
1 of 10
Sold through salons, and 6 products that do the same job cost less. Part of what you pay for is where it is sold.
How the score is counted
- 6 products that do the same job cost less per ounce
- Costs more per ounce than 79% of the 280 scalp treatments we’ve priced
- No conditioning agents up front in the formula
- No oils or butters in the working zone either
- Conditioning agents up frontWhat makes wet hair comb through.3 pts
- Oils or butters in the working zoneSoftens the strand rather than just coating it.2 pts
- Slip for detanglingReduces the force it takes to comb wet hair.2 pts
- A humectantBinds water into the hair.1 pt
- A pH adjusterBrings the formula to the acidic pH hair prefers.1 pt
- Fragrance kept out of the top eightScent as a finishing touch, not a major share.1 pt
The formula score measures completeness for the job: a weighted share of the systems this product type is usually built around that we find in this list. It does not rate how well the product works or its quality, and it never compares across product types.
Does the same job, for less
Formulas that do the same things (cleanse, condition, coat or hold) for less per ounce. Scent, texture and where you buy them can still differ.
MizaniSame function
Scalp Care Soothing Serum
$2.83/oz $18.27/oz less
- Fragrance-free
- Protein-free
- Lightweight
- Differs
KloraneSame function
Intense Strengthening Serum with Quinine
$10.15/oz $10.95/oz less
- Protein-free
- Lightweight
- Silicone-free
- Differs
PacificaLowest cost per oz
Rosemary Apple Cider Scalp Detox Tonic
$1.99/oz $19.11/oz less
- Protein-free
- Lightweight
- Silicone-free
- Differs
See more alternatives in the product library
These products do a similar job. We haven’t matched them to you. Find the one that fits your hair, routine and budget
Final decision
Should you buy it?
Similar results available for lessBest user
Hair that stiffens on protein who want a protein-free formula and something that will not weigh hair down
Biggest tradeoff
Worth skipping for anyone sensitive to fragrance, very dry or high-damage hair, or vegan and cruelty-free shopping
Best alternative if not
Mizani Scalp Care Soothing Serum for similar results at a lower price
We do not sell products or take placement fees. This page states what the formula and the prices show; the consultation is what matches it to a person.
Claims check
What the brand says, and what the formula shows
Claims are quoted from the brand. We mark a claim supported, partly supported or conflicting only when the ingredient list speaks to it. Everything else stays "stated by the brand". That isn’t a criticism: most claims can’t be checked from a label.
1
SupportedBacked by ingredients
0
Partly supportedSome supporting logic
0
Stated by brandNo clear evidence
0
Potential conflictFormula works against claim
How to read this
We look at the first 10–15 ingredients and what they do in a formula, not at the marketing. If the list doesn't speak to a claim, we don't assume.
Reviewers
What people report
Themes that come up again and again in sourced reviews, written by our researchers in their own words. We don’t store or scrape star ratings.
Users often find the liquid light and non-greasy for overnight application.
US exact-product reviewer accounts; promotional sampling appears in the corpus. Review IDs: 1172115598, 1171689932, 1171580825, 1169661644Leaking bottles and difficult dispensing recur in packaging complaints.
US exact-product reviewer accounts; promotional sampling appears in the corpus. Review IDs: 1169690823, 1169555383, 1168103122, 1148458466Some users report scalp tenderness, itching or a burning sensation.
US exact-product reviewer accounts; promotional sampling appears in the corpus. Review IDs: 1172271437, 1169507711, 1153761231Reports of fuller-looking hair are mixed with reports of no visible difference after several weeks.
US exact-product reviewer accounts; promotional sampling appears in the corpus. Review IDs: 1175637429, 1171789190, 1172271437, 1169661644, 1148458337More from Nioxin
How this page was made
- Everything above comes from our researched product record: identity, the ingredient list as printed, the brand's own claims, dated prices and review themes our researchers wrote in their own words. No part of this page is written by hand for one product.
- The value band is a fixed label over two stored numbers: this product’s cost per ounce as a percentile of every product of this type we have priced, each at the size it is most often sold in, and how many products we score as doing the same job cost at least a quarter less per ounce.
- Both scores out of ten are defined on this page. The formula score is completeness for the job, computed from a fixed per-format checklist shown beneath the gauge; the price score is cost per ounce against every product of this type we have priced.
- The "Is this right for you?" panel reads only your own consultation answers, and it applies exactly the filters our recommendation engine applies. It is computed when you load the page and is never stored on it.
- 6 sources consulted for this product (2 manufacturer or regulatory, 1 retailer, 3 editorial), last checked 2026-09-13.
- Ingredient references are linked for 10 of 13 product-aware annotations on this page. Fit notes are general formulation guidance. They aren’t a verdict on the finished product or on you.
- We haven’t tested this product in a lab, and we don’t physically test your hair. Formula readings come from the ingredient list. Claims about how it behaves are labelled as the brand's.
- Ingredient order tells you relative amount only above roughly 1%. Prices are what we saw on the dates shown and can change.
- Ingredient names link to our ingredient library, where each entry shows what it does, which product types use it, and where it usually sits on a label across everything we have researched.
- This is cosmetic information, not medical advice, and nothing here diagnoses or treats a health condition.
- Formula readings: derivation v23. Record last updated 2026-10-03.
