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Head & Shoulders

Irritation Relief 2 IN 1 Dandruff Shampoo and Conditioner

Shampoo / Everyday cleanser, balanced

  • Shampoo
  • Protein-free
  • Not cruelty-free · PETA-listed
Size12.5 fl oz (370 ml)
Price$8.99seen at one store · 12.5 oz
Price / oz$0.72/ozat 12.5 oz

Add it to your products. We’ll tell you if it’s ever recalled.

Scent:

The ingredient list declares fragrance. What it smells of is not stated, and we do not guess.

Manufacturer page: smartlabel.pg.com

Personal fit

Is this right for you?

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Lower cost than most shampoos

$0.72/oz at 12.5 oz, less than 78% of the 1544 shampoos , which mostly run $0.79–3.04/oz. The cost less.

Price and stores

Great for

Flaking scalpsit has an over-the-counter active
Protein-sensitive hairthat stiffens when protein is added
Very dry hairno fast-drying alcohol in the list
A wide range of haira middle-of-the-range weight
Tight budgetsit sits in the lower price tiers

Maybe skip if

this product has a scent
Sulfate-free routinesit uses a sulfate detergent
Curly-method routinesthese silicones need a detergent to remove
Hair that needs proteinthere is none in this list
Hard waterno chelator here to bind the minerals
Non-medicated routinesthis is an over-the-counter drug as well as a cosmetic

How much cleansing you need depends on how fast your scalp gets oily, how much product you layer and your water. The consultation works that out.

What the formula actually does

Read from the label, not the marketing

Each row says where it comes from: F means we derived it from this product’s own ingredient list, S means it is a claim the brand makes that the formula neither confirms nor contradicts.

Cleansing strength Moderate

Removes oil and product; leaves some conditioning behind.

Expected lather High

Thick foam that spreads quickly through the hair.

Slip and detangling Some

Some slip, mostly from esters or silicones rather than conditioners.

Water-binding (humectants) Low

Humectants appear, but low enough to be a minor part.

Scalp active zinc pyrithione

Carries an over-the-counter scalp active, listed under Drug Facts.

Hard-water defence None

No chelating agent in the list.

Needs detergent to remove Yes

Water-insoluble silicones or waxes: a detergent wash is what removes them.

Protein None

No protein or amino acids in the list.

Fragrance Prominent

Fragrance is in the first eight ingredients, so it makes up a larger share of the formula.

from the formula stated by the brand reported by reviewers Scale: 1 dot low · 5 dots high, within this product type.

Ingredients that matter

The ingredients that change a decision

The workhorse ingredients, plus anything lower down that changes a decision. The chips name what an ingredient does. They are not safety scores, and no ingredient here is rated good or bad on its own.

IngredientWhat it doesWhy it mattersChip
Zinc PyrithionePyrithione Zinc (1%) active The over-the-counter active Active
Water solvent The base everything else is dissolved in Neutral
Sodium Lauryl Sulfate sulfate cleanser — Cleanses
Glycol Distearate opacifier Makes the product look creamy Softens
Zinc Carbonate mineral Adds texture or opacity Neutral
Sodium Chloridesodiumchloride salt Thickens the formula Stabilizes
Fragrance fragrance The scent Fragrance
Cocamidopropyl Betaine amphoteric cleanser — Cleanses
Dimethicone silicone A little smoothing and shine Buildup
Piroctone Olamine active A secondary active Active
What the list leaves out, and what it carriesThe list carries no drying alcohols. No protein: a moisture formula, not a repair one. Fragrance is on the label. Water-insoluble silicones that need a detergent wash to remove.
Full ingredient list (21)

In the US, ingredients above 1% are listed from most to least. Below 1% they can appear in any order. Each note keeps three things apart: what the ingredient generally does, its role in this type of product, and what its position can tell you.

  • 1 Zinc Pyrithione · Pyrithione Zinc (1%)
    General function

    An over-the-counter anti-dandruff active that reduces the yeast associated with flaking. Its percentage is stated in the drug facts panel.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    PubChem
    • active
  • 2 Water
    General function

    The base of almost every rinse-off and cream hair product. It carries everything else and is normally the first ingredient on the label.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    • solvent
  • 3 Sodium Lauryl Sulfate
    General function

    A high-foaming, strongly cleansing detergent. It clears build-up thoroughly and is the harsher of the two common sulfates.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    May suitBuild-up-sensitive routines

    A sulfate detergent can lift deposited silicone, wax and styling films, which is what resets a routine before build-up is visible.

    May suitFine or easily flattened hair

    Fine hair that goes limp under conditioning films usually reads a full detergent wash as volume returning.

    May not suitDry, coarse, or high-porosity hair

    Coarse and high-porosity hair loses water quickly on its own; an efficient detergent removes the surface oils that were slowing that down.

    Indian Journal of Dermatology
    • sulfate cleanser
    • cleanser
  • 4 Glycol Distearate
    General function

    A wax that gives shampoo its pearly look and a slightly richer feel.

    Supporting ingredient

    Listed in positions 4–8, it likely makes a meaningful contribution alongside the formula's main ingredients.

    May suitFrizz-prone, damaged, or high-friction hair

    Emollients fill and smooth the surface of the strand, which lowers the friction that lifts the cuticle and reads as roughness.

    PubChem
    • opacifier
    • emollient
  • 5 Zinc Carbonate
    General function

    A zinc salt that accompanies zinc pyrithione in some anti-dandruff formulas.

    Supporting ingredient

    Listed in positions 4–8, it likely makes a meaningful contribution alongside the formula's main ingredients.

    PubChem
    • mineral
  • 6 Sodium Chloride · sodiumchloride
    General function

    Table salt. In shampoo it is used to thicken the liquid, not to treat the hair.

    Supporting ingredient

    Listed in positions 4–8, it likely makes a meaningful contribution alongside the formula's main ingredients.

    PubChem
    • salt
    • thickener
  • ▾Below about here, the order stops meaning much. These are usually used at 1% or less.
  • 7 Fragrance
    General function

    An undisclosed blend of scent ingredients. Regulations let it stay unlisted, so a fragrance-free product is the only way to be certain what is not in it.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May not suitFragrance-sensitive routines

    Declared fragrance. On a fragrance-sensitive routine this is the line that decides it, wherever it sits on the label.

    • fragrance
    • declared fragrance
  • 8 Cocamidopropyl Betaine
    General function

    A mild coconut-derived co-cleanser that boosts foam and softens the effect of stronger detergents. It appears in most shampoos, gentle or not.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitDry, coarse, or high-porosity hair

    Mild cleansing leaves more surface lubrication in place on hair that dries out quickly.

    May not suitBuild-up-sensitive routines

    The mildest detergents are also the least complete: a routine that deposits films needs something stronger periodically.

    DependsVery dry or highly damaged hair

    Among the mildest detergents in use — it is what baby shampoos are built on — but it is almost always the second detergent in a formula. How much a wash strips is still decided by the primary detergent listed above it.

    Indian Journal of Dermatology
    • amphoteric cleanser
    • secondary cleanser
    • cleanser
  • 9 Sodium Xylenesulfonate · sodiumxylenesulfonate
    • solubilizer
  • 10 Dimethicone
    General function

    The most common conditioning silicone. It coats the strand for shine, slip, and frizz control, and needs a detergent (not just water) to wash out.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitClimate-sensitive or frizz-prone hair

    A surface film slows how quickly humidity reaches the cortex, which is what limits swelling-driven frizz in damp air.

    May suitFrizz-prone, damaged, or high-friction hair

    Lays a smooth film along the cuticle, which lowers combing friction and flattens the surface irregularities that read as frizz.

    • silicone
    • emollient
    • conditioning agent
  • 11 sodiumbenzoate
  • 12 guar hydroxypropyltrimoniumchloride
  • 13 Piroctone Olamine
    • active
  • 14 Glycerin
    General function

    Glycerin, also called glycerol, attracts moisture and mixes completely with water.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitDry, coarse, or high-porosity hair

    High-porosity hair loses water fast; a humectant holds some of it in place for longer than the wash itself would.

    May suitVery dry or highly damaged hair

    Binds water into the outer layers of the strand, and water is what makes dry hair flexible again rather than brittle.

    DependsClimate-sensitive or frizz-prone hair

    Water moves both ways. Measured across concentrations, glycerin solutions give water up in some conditions and take it from the air in others. What it does for you depends on how much of it is there and on the air around it.

    Scientific Reports
    • humectant
  • 15 Sodiumlaureth sulfate
  • 16 Butylene Glycol
    General function

    A light humectant and carrier that helps extracts dissolve.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitFine or easily flattened hair

    Light and water-binding rather than oily, so it adds less weight than oils or butters do.

    May suitVery dry or highly damaged hair

    A small water-binding solvent. It holds moisture and helps the rest of the formula spread evenly over the strand.

    DependsClimate-sensitive or frizz-prone hair

    A humectant follows the air: it holds water in humid conditions and can give it up in very dry ones. Climate decides what it does more than the label does.

    PubChem
    • humectant
    • solvent
  • 17 Magnesium carbonate hydroxide
  • 18 Pentylene Glycol
    General function

    A humectant that also helps preserve the formula, often used where a brand wants a short preservative list.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitFine or easily flattened hair

    Light and water-binding rather than oily, so it adds less weight than oils or butters do.

    May suitVery dry or highly damaged hair

    A small water-binding solvent. It holds moisture and helps the rest of the formula spread evenly over the strand.

    DependsClimate-sensitive or frizz-prone hair

    A humectant follows the air: it holds water in humid conditions and can give it up in very dry ones. Climate decides what it does more than the label does.

    PubChem
    • humectant
    • solvent
    • preservative
  • 19 neosetophoma cerealis extract
  • 20 aloe barbadensis leafjuice
  • 21 Niacinamide
    General function

    Vitamin B3, used in scalp products for conditioning claims.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitFrizz-prone, damaged, or high-friction hair

    Deposits a lubricating layer that makes combing easier, which is most of what stops mechanical damage adding to frizz.

    PubChem
    • vitamin
    • conditioning agent

What the whole list adds up to

  • 3 solvents
  • 3 humectants
  • 2 actives
  • 2 cleansers
  • 2 emollients
  • 2 conditioning agents
  • 1 sulfate cleanser
  • 1 opacifier
  • 1 mineral
  • 1 salt
  • 1 thickener
  • 1 fragrance
  • 1 declared fragrance
  • 1 amphoteric cleanser

Ingredient list captured 2026-10-10. Formulas change, so check the package in your hand when an ingredient matters to you.

Price · 12.5 oz

Seen at $8.99 1 store · checked Oct 10
Good value under $6 Under $0.47/oz it costs less than three-quarters of the 8 products we score as doing the same job

Priced above the products that do the same job. Stores sell it above the $6 line; products that do this job typically go for about $7 at this size.

Show the price ladder
Where we’ve seen it2 listings · 1 store
  • walmart
    $8.99
    12.5 oz · $0.72/oz
    Oct 10Lowest per oz
  • walmart
    $8.99
    12.5 oz · $0.72/oz
    Oct 10

Sorted by price per ounce. Dated observations from our research, not live prices. Direct store pages, no affiliate links. We don’t sell this product.

How we work this out
  1. 12.5 oz is the size stores list most often; every comparison on this page is made at it. Other sizes are shown in the Sizes row and the store list.
  2. Seen at $8.99 is the price we have observed for the 12.5 oz. We need three stores before we call a price commonly seen.
  3. Good value under $6 comes from the 8 products we score as doing the same job as this one. A quarter of them cost less than $0.47/oz; at 12.5 oz that is $6. Under that line you are paying less than most of them.
  4. About $7 is what those same products typically cost at this size: the midpoint of their prices per ounce, scaled to 12.5 oz.

Formula

Formula score
4 of 10

Low cost per ounce, with a short formula: there is no slip for detangling here, and that is a system most shampoos carry.

How the score is counted
  • 4 products that do the same job cost less per ounce
  • Costs less per ounce than 78% of the 1544 shampoos we’ve priced
  • No slip for detangling in the formula
  • No hard-water chelator either
  • A working detergent systemWhat actually removes oil and product.3 pts
  • Slip for detanglingReduces the force it takes to comb wet hair.2 pts
  • A humectantBinds water into the hair.1 pt
  • A hard-water chelatorBinds the minerals that dull hair in hard water.1 pt
  • A pH adjusterBrings the formula to the acidic pH hair prefers.1 pt
  • No detergent-dependent filmNothing that needs a clarifying wash to remove.1 pt
  • Fragrance kept out of the top eightScent as a finishing touch, not a major share.1 pt

The formula score measures completeness for the job: a weighted share of the systems this product type is usually built around that we find in this list. It does not rate how well the product works or its quality, and it never compares across product types.

Does the same job, for less

Formulas that do the same things (cleanse, condition, coat or hold) for less per ounce. Scent, texture and where you buy them can still differ.

Head & ShouldersLowest cost per oz Ginger Anti-Dandruff 2 in 1 Shampoo and Conditioner $0.44/oz $0.28/oz less
  • Scalp active
· Close function
Function
  • Water-binding (humectants)
Also
  • Masstige tier
  • 28.2 oz bottle
Compare
Head & ShouldersLighter feel Itch Relief 2 IN 1 Dandruff Shampoo & Conditioner $0.48/oz $0.24/oz less
  • Scalp active
  • Protein-free
  • Deep clean
· Close function
Function
  • Cleansing strength
  • Slip and detangling
  • Film formers
Also
  • 20.7 oz bottle
Compare
Head & ShouldersLighter feel Mens 2 in 1 Dandruff Shampoo and Conditioner, Bourbon $0.44/oz $0.28/oz less
  • Scalp active
  • Protein-free
  • Deep clean
· Close function
Function
  • Cleansing strength
  • Slip and detangling
  • Film formers
Also
  • Masstige tier
  • 28.2 oz bottle
Compare

See more alternatives in the product library

These products do a similar job. We haven’t matched them to you. Find the one that fits your hair, routine and budget

Suits every hair pattern

Final decision

Should you buy it?

Only for a specific need
Best user

Flaking scalps, looking for an over-the-counter scalp active and a protein-free formula

Biggest tradeoff

Less suited to anyone sensitive to fragrance, sulfate-free routines and fresh keratin treatments, or curly-method routines

We do not sell products or take placement fees. This page states what the formula and the prices show; the consultation is what matches it to a person.

More from Head & Shoulders

How this page was made

  • Everything above comes from our researched product record: identity, the ingredient list as printed, the brand's own claims, dated prices and review themes our researchers wrote in their own words. No part of this page is written by hand for one product.
  • The value band is a fixed label over two stored numbers: this product’s cost per ounce as a percentile of every product of this type we have priced, each at the size it is most often sold in, and how many products we score as doing the same job cost at least a quarter less per ounce.
  • Both scores out of ten are defined on this page. The formula score is completeness for the job, computed from a fixed per-format checklist shown beneath the gauge; the price score is cost per ounce against every product of this type we have priced.
  • The "Is this right for you?" panel reads only your own consultation answers, and it applies exactly the filters our recommendation engine applies. It is computed when you load the page and is never stored on it.
  • 4 sources consulted for this product (1 manufacturer or regulatory, 1 retailer, 2 editorial), last checked 2026-10-10.
  • Ingredient references are linked for 7 of 9 product-aware annotations on this page. Fit notes are general formulation guidance. They aren’t a verdict on the finished product or on you.
  • We haven’t tested this product in a lab, and we don’t physically test your hair. Formula readings come from the ingredient list. Claims about how it behaves are labelled as the brand's.
  • Ingredient order tells you relative amount only above roughly 1%. Prices are what we saw on the dates shown and can change.
  • Ingredient names link to our ingredient library, where each entry shows what it does, which product types use it, and where it usually sits on a label across everything we have researched.
  • This is cosmetic information, not medical advice, and nothing here diagnoses or treats a health condition.
  • Formula readings: derivation v23. Record last updated 2026-10-11.

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