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Neutrogena

T/Sal Therapeutic Shampoo

Shampoo / Clarifying, deep-cleaning

  • Shampoo
  • Sulfate-free
  • Silicone-free
  • Not cruelty-free · PETA-listed
Size4.5 fl oz
Price$8–11commonly seen · 4.5 oz
Price / oz$1.97/ozat 4.5 oz

Add it to your products. We’ll tell you if it’s ever recalled.

Scent:

No added fragrance, no scenting essential oils, and no declared fragrance allergens on the list.

Listing used for research: target.com

Personal fit

Is this right for you?

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$49 with 60 days of follow-up questions and plan updates

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Upper-mid price for a shampoo

$1.97/oz at 4.5 oz, more than 60% of the 1544 shampoos , which mostly run $0.79–3.04/oz. The cost less.

Price and stores

Great for

Flaking scalpsit has an over-the-counter active
no fragrance (parfum) on the label
free of strong smells
Colour-treated hairthat fades faster in a sulfate wash
Protein-sensitive hairthat stiffens when protein is added
Fast-oiling scalpsthat need a real reset wash

Maybe skip if

Dry or damaged haira strong detergent system strips as it cleans
Hair that needs proteinthere is none in this list
Hard waterno chelator here to bind the minerals
Non-medicated routinesthis is an over-the-counter drug as well as a cosmetic
Vegan and cruelty-freeour record does not support both claims here
If scent matters to younothing is added here

How much cleansing you need depends on how fast your scalp gets oily, how much product you layer and your water. The consultation works that out.

What the formula actually does

Read from the label, not the marketing

Each row says where it comes from: F means we derived it from this product’s own ingredient list, S means it is a claim the brand makes that the formula neither confirms nor contradicts.

Cleansing strength Strong

A reset wash that removes oil, buildup, and most residue.

Expected lather High

Thick foam that spreads quickly through the hair.

Slip and detangling High

Conditioning agents sit high in the list, so this is a detangling formula.

Water-binding (humectants) Moderate

Humectants in the working part of the formula.

Scalp active salicylic acid, 3%

Carries an over-the-counter scalp active, listed under Drug Facts.

Hard-water defence None

No chelating agent in the list.

Needs detergent to remove No

Nothing here needs a detergent wash to remove.

Protein None

No protein or amino acids in the list.

Fragrance None listed

No fragrance is listed.

from the formula stated by the brand reported by reviewers Scale: 1 dot low · 5 dots high, within this product type.

Ingredients that matter

The ingredients that change a decision

The workhorse ingredients, plus anything lower down that changes a decision. The chips name what an ingredient does. They are not safety scores, and no ingredient here is rated good or bad on its own.

IngredientWhat it doesWhy it mattersChip
Water solvent The base everything else is dissolved in Neutral
Sodium C14-16 Olefin Sulfonate olefin sulfonate cleanser — Cleanses
Cocamidopropyl Betaine amphoteric cleanser — Cleanses
Sodium Chloride salt Thickens the formula Stabilizes
Polyquaternium-22 film former Lays down the film that holds a shape Detangles
Sodium Citrate pH adjuster Fine-tunes the pH pH balancer
Hexylene Glycol solvent Carrier for the rest of the formula Moisturizes
Sodium Lauroyl Sarcosinate mild anionic cleanser — Cleanses
What the list leaves out, and what it carriesThe list carries no sulfates, silicones, or drying alcohols. No protein: a moisture formula, not a repair one. Carries an over-the-counter scalp active (salicylic acid 3%).
Full ingredient list (11)

In the US, ingredients above 1% are listed from most to least. Below 1% they can appear in any order. Each note keeps three things apart: what the ingredient generally does, its role in this type of product, and what its position can tell you.

  • 1 Water
    General function

    The base of almost every rinse-off and cream hair product. It carries everything else and is normally the first ingredient on the label.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    • solvent
  • 2 Sodium C14-16 Olefin Sulfonate
    General function

    A strong non-sulfate detergent used in "sulfate-free" shampoos. It cleans about as thoroughly as a sulfate despite the label difference.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    May suitBuild-up-sensitive routines

    A strong detergent with no sulfate on the label. It removes deposited films about as completely as a sulfate does.

    May not suitVery dry or highly damaged hair

    Sulfate-free on the label is a naming fact, not a mildness one: this is an efficient detergent, and hair short of moisture can feel it.

    PubChem
    • olefin sulfonate cleanser
    • cleanser
  • 3 Cocamidopropyl Betaine
    General function

    A mild coconut-derived co-cleanser that boosts foam and softens the effect of stronger detergents. It appears in most shampoos, gentle or not.

    Leading ingredient

    Listed in the first three ingredients, it is likely a structural part of this formula.

    May suitDry, coarse, or high-porosity hair

    Mild cleansing leaves more surface lubrication in place on hair that dries out quickly.

    May not suitBuild-up-sensitive routines

    The mildest detergents are also the least complete: a routine that deposits films needs something stronger periodically.

    DependsVery dry or highly damaged hair

    Among the mildest detergents in use — it is what baby shampoos are built on — but it is almost always the second detergent in a formula. How much a wash strips is still decided by the primary detergent listed above it.

    Indian Journal of Dermatology
    • amphoteric cleanser
    • secondary cleanser
    • cleanser
  • 4 Sodium Chloride
    General function

    Table salt. In shampoo it is used to thicken the liquid, not to treat the hair.

    Supporting ingredient

    Listed in positions 4–8, it likely makes a meaningful contribution alongside the formula's main ingredients.

    PubChem
    • salt
    • thickener
  • 5 Polyquaternium-22
    General function

    A conditioning polymer that adds slip and helps hold moisture on the strand.

    Supporting ingredient

    Listed in positions 4–8, it likely makes a meaningful contribution alongside the formula's main ingredients.

    May suitCurls or waves needing flexible hold

    Cationic polymers hold a curl loosely and stay soft, which is why they turn up in definition products rather than firm-hold ones.

    May suitFrizz-prone, damaged, or high-friction hair

    A cationic polymer stays on the hair through rinsing, which is what keeps static and combing friction down after the wash.

    May suitMaximum-hold styling

    Film formers are what hold a style: they dry into a connected film across the strands so the shape resists movement.

    • film former
    • polymer
    • conditioning agent
  • ▾Below about here, the order stops meaning much. These are usually used at 1% or less.
  • 6 Sodium Citrate
    General function

    Used with citric acid to hold the formula at a steady, slightly acidic pH. It also binds a little hard-water mineral.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitBuild-up-sensitive routines

    Binds the calcium and magnesium in hard water, which is what stops mineral deposits accumulating on the strand wash after wash.

    May suitGray, silver, or brass-prone hair

    Copper and iron carried in tap water deposit on the strand and read as a dull, warm cast on gray or light hair. A chelator holds those metals in solution so the wash carries them off.

    DependsFrizz-prone, damaged, or high-friction hair

    pH adjusters are how a formula is brought to a chosen acidity, and an acidic formula keeps the cuticle lying flatter than an alkaline one. Which way this one moves the pH depends on the formula, and the finished pH is not on the label.

    PubChem
    • pH adjuster
    • hard-water chelator
  • 7 Hexylene Glycol
    General function

    A solvent that keeps other ingredients dissolved and helps preservatives work.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitFine or easily flattened hair

    Light and water-binding rather than oily, so it adds less weight than oils or butters do.

    May suitVery dry or highly damaged hair

    A small water-binding solvent. It holds moisture and helps the rest of the formula spread evenly over the strand.

    DependsClimate-sensitive or frizz-prone hair

    A humectant follows the air: it holds water in humid conditions and can give it up in very dry ones. Climate decides what it does more than the label does.

    PubChem
    • solvent
    • humectant
  • 8 Sodium Lauroyl Sarcosinate
    General function

    A gentle cleanser that leaves a soft after-feel; often paired with stronger detergents.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitCurls or waves needing flexible hold

    The detergent class most curl routines are built around: it lathers and cleanses without stripping the strand back to bare.

    May suitDry, coarse, or high-porosity hair

    A gentler detergent leaves more of the surface oil that slows water loss from coarse or porous hair.

    May suitVery dry or highly damaged hair

    Cleanses with less sebum removal than a sulfate detergent, so hair that is short of moisture keeps more of it through the wash.

    PubChem
    • mild anionic cleanser
    • cleanser
  • 9 Linoleamidopropyl PG-Dimonium Chloride Phosphate
    General function

    A conditioning agent that carries fatty acids onto the strand for slip without heaviness.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitFrizz-prone, damaged, or high-friction hair

    A cationic conditioning agent: it binds to the damaged, negatively charged parts of the cuticle and lowers combing friction there.

    May suitVery dry or highly damaged hair

    The class that does the detangling in a conditioner. It deposits lubrication where the cuticle is worn.

    DependsBuild-up-sensitive routines

    Substantive by design. A routine with no detergent wash gives it nothing to leave with.

    PubChem
    • conditioning agent
  • 10 Sodium Hydroxide
    General function

    A strong base used in trace amounts to raise pH; fully neutralised in the finished product.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    DependsFrizz-prone, damaged, or high-friction hair

    The alkali half of a pH-adjusting pair, used in small amounts to bring a formula up to its target rather than to make it alkaline. Alkaline conditions raise the fibre's surface charge and lift the scales — but the finished pH is not on the label.

    International Journal of Trichology
    • pH adjuster
  • 11 Citric Acid
    General function

    Used to bring the product to a slightly acidic pH, which helps the cuticle lie flat. It is almost always near the end of the list.

    Estimated lower-concentration zone

    It appears around or below the estimated 1% line, where label order no longer indicates relative amount; its role may be minor or technical.

    May suitBuild-up-sensitive routines

    Holds hard-water minerals in solution so they rinse away instead of depositing on the hair.

    May suitFrizz-prone, damaged, or high-friction hair

    The acid side of pH adjustment, and the reason it matters is measured: alkaline formulas raise the fibre's surface negative charge, increase friction between strands and lift the scales, while lower-pH ones do the reverse.

    May suitGray, silver, or brass-prone hair

    Where a warm cast comes from water minerals rather than from the hair itself, holding those metals in solution is what removes it.

    International Journal of Trichology
    • pH adjuster
    • hard-water chelator

What the whole list adds up to

  • 3 cleansers
  • 3 pH adjusters
  • 2 solvents
  • 2 conditioning agents
  • 2 hard-water chelators
  • 1 olefin sulfonate cleanser
  • 1 amphoteric cleanser
  • 1 secondary cleanser
  • 1 salt
  • 1 thickener
  • 1 film former
  • 1 polymer
  • 1 humectant
  • 1 mild anionic cleanser

Drug facts actives

  • salicylic acid 3%

This product is an over-the-counter drug as well as a cosmetic. It treats a cosmetic scalp condition; it does not diagnose or treat disease.

Ingredient list captured 2026-08-21. Formulas change, so check the package in your hand when an ingredient matters to you.

Price · 4.5 oz

Commonly seen $8–11 Midpoint $8.84 · 4 stores · checked Aug 30
Good value under $5 Under $1.15/oz it costs less than three-quarters of the 8 products we score as doing the same job

Priced above the products that do the same job. Stores sell it above the $5 line; products that do this job typically go for about $5 at this size.

Show the price ladder
Where we’ve seen it4 listings · 4 stores
  • Walmart
    $7.77
    4.5 oz · $1.73/oz
    Aug 30Lowest per ozSale · was $14.67
  • Target
    $7.79
    4.5 oz · $1.73/oz
    Aug 30
  • CVS
    $9.89
    4.5 oz · $2.20/oz
    Aug 30
  • Walgreens
    $12.49
    4.5 oz · $2.78/oz
    Aug 30

Sorted by price per ounce. Dated observations from our research, not live prices. Direct store pages, no affiliate links. We don’t sell this product.

How we work this out
  1. 4.5 oz is the size stores list most often; every comparison on this page is made at it. Other sizes are shown in the Sizes row and the store list.
  2. Commonly seen is the middle half of current prices for the 4.5 oz at recognised stores. We leave out the cheapest and most expensive quarters, so one sale or one overpriced listing can’t move it.
  3. Good value under $5 comes from the 8 products we score as doing the same job as this one. A quarter of them cost less than $1.15/oz; at 4.5 oz that is $5. Under that line you are paying less than most of them.
  4. About $5 is what those same products typically cost at this size: the midpoint of their prices per ounce, scaled to 4.5 oz.

Formula

Formula score
10 of 10

A complete formula at an ordinary price: mid-range per ounce among shampoos, with the working systems in place.

How the score is counted
  • 5 products that do the same job cost less per ounce
  • Costs more per ounce than 60% of the 1544 shampoos we’ve priced
  • Covers 7 of the 7 things a shampoo should do
  • Reviewers mention 3 recurring complaints
  • A working detergent systemWhat actually removes oil and product.3 pts
  • Slip for detanglingReduces the force it takes to comb wet hair.2 pts
  • A humectantBinds water into the hair.1 pt
  • A hard-water chelatorBinds the minerals that dull hair in hard water.1 pt
  • A pH adjusterBrings the formula to the acidic pH hair prefers.1 pt
  • No detergent-dependent filmNothing that needs a clarifying wash to remove.1 pt
  • Fragrance kept out of the top eightScent as a finishing touch, not a major share.1 pt

The formula score measures completeness for the job: a weighted share of the systems this product type is usually built around that we find in this list. It does not rate how well the product works or its quality, and it never compares across product types.

Does the same job, for less

Formulas that do the same things (cleanse, condition, coat or hold) for less per ounce. Scent, texture and where you buy them can still differ.

NeutrogenaSame function Scalp Therapy Anti-Dandruff Extra Strength $1.17/oz $0.80/oz less
  • Scalp active
  • Fragrance-free
  • Unscented
Differs
  • Masstige tier
  • 12 oz bottle
Compare
NeutrogenaLowest cost per oz Scalp Therapy Itchy Scalp Shampoo $1.03/oz $0.94/oz less
  • Scalp active
  • Sulfate-free
  • Protein-free
· Same function
Differs
  • Mint scent, not unscented
  • 12 oz bottle
Compare
NeutrogenaClose function T/Sal+ 3% Salicylic Acid Anti-Dandruff Shampoo for Dry, Itchy Scalp Control $1.19/oz $0.78/oz less
  • Scalp active
  • Fragrance-free
  • Unscented
Function
  • Slip and detangling
Also
  • 8 oz bottle
Compare

See more alternatives in the product library

These products do a similar job. We haven’t matched them to you. Find the one that fits your hair, routine and budget

Suits every hair pattern

Final decision

Should you buy it?

A solid pick for the hair it suits
Best user

Flaking scalps who want an over-the-counter scalp active and a formula with no added fragrance

Biggest tradeoff

Worth skipping for dry or damaged hair, soft, over-stretchy hair that needs protein, or hard water without a chelating wash

We do not sell products or take placement fees. This page states what the formula and the prices show; the consultation is what matches it to a person.

Claims check

What the brand says, and what the formula shows

Claims are quoted from the brand. We mark a claim supported, partly supported or conflicting only when the ingredient list speaks to it. Everything else stays "stated by the brand". That isn’t a criticism: most claims can’t be checked from a label.

1
SupportedBacked by ingredients
0
Partly supportedSome supporting logic
0
Stated by brandNo clear evidence
0
Potential conflictFormula works against claim
Controls the symptoms of dandruff and seborrheic dermatitis

It carries an over-the-counter anti-dandruff active.

—

Supported

A recognised active does the work.

How to read this

We look at the first 10–15 ingredients and what they do in a formula, not at the marketing. If the list doesn't speak to a claim, we don't assume.

Reviewers

What people report

Themes that come up again and again in sourced reviews, written by our researchers in their own words. We don’t store or scrape star ratings.

Reviewers report the shampoo controls flaking and scalp build-up and continues working after rinse-out

Reviewers using it as a regular/exclusive shampoo over months report hair becoming drier, more brittle, and thinner

extended/exclusive use

A reviewer reported visible gray-hair discoloration developing with use, raising a color-safety concern

Reviewers with fine hair report the shampoo leaves hair feeling dry and damaged after use

fine hair

More from Neutrogena

How this page was made

  • Everything above comes from our researched product record: identity, the ingredient list as printed, the brand's own claims, dated prices and review themes our researchers wrote in their own words. No part of this page is written by hand for one product.
  • The value band is a fixed label over two stored numbers: this product’s cost per ounce as a percentile of every product of this type we have priced, each at the size it is most often sold in, and how many products we score as doing the same job cost at least a quarter less per ounce.
  • Both scores out of ten are defined on this page. The formula score is completeness for the job, computed from a fixed per-format checklist shown beneath the gauge; the price score is cost per ounce against every product of this type we have priced.
  • The "Is this right for you?" panel reads only your own consultation answers, and it applies exactly the filters our recommendation engine applies. It is computed when you load the page and is never stored on it.
  • 4 sources consulted for this product (3 manufacturer or regulatory, 1 retailer, 0 editorial), last checked 2026-08-25.
  • Ingredient references are linked for 8 of 9 product-aware annotations on this page. Fit notes are general formulation guidance. They aren’t a verdict on the finished product or on you.
  • We haven’t tested this product in a lab, and we don’t physically test your hair. Formula readings come from the ingredient list. Claims about how it behaves are labelled as the brand's.
  • Ingredient order tells you relative amount only above roughly 1%. Prices are what we saw on the dates shown and can change.
  • Ingredient names link to our ingredient library, where each entry shows what it does, which product types use it, and where it usually sits on a label across everything we have researched.
  • This is cosmetic information, not medical advice, and nothing here diagnoses or treats a health condition.
  • Formula readings: derivation v23. Record last updated 2026-10-19.

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