AMINO ACID
Histidine
- amino acid
One of the amino acids that make up hair protein, added for moisture binding.
- products in our library
- 161
- of researched products
- 4%
- on the label, in our conditioners
- usually #14
- most common in
- Conditioner
- in water
- Water-soluble
At a glance
Four named levels, read from this ingredient’s chemical class, its charge, its solubility, or where it sits on the labels we have. More dots means more of the property named — never “better”.
How much of it is left on hair between washes.
What it takes to get it off the hair again.
Smaller fragments travel further into the strand.
Read from where it sits on the labels we have, not from the molecule.
| Property | Level | Out of |
|---|---|---|
| Buildup risk | Low | 1 of 5 |
| Rinse-out behaviour | Rinses clean | 5 of 5 |
| Fragment size | Smallest | 1 of 5 |
| Stiffening potential | Slight | 2 of 5 |
What it does for a formula
What Histidine does
The general function first, then how the role changes by product type where we have researched it.
Small enough to travel further into the strand than a whole protein can.
Water alone removes it, so it does not accumulate between washes.
Charge
Charge is not recorded for this ingredient.
Solubility
Rinses out with water alone — it does not accumulate on hair between washes.
Where it appears
Where it appears
One row per product category in our library: how many products list it, what share of that category that is, and where it typically sits on the label.
| Product type | How common | Typical position on label ? |
|---|---|---|
Conditioner
52 products
|
secondary · #14 | |
Shampoo
42 products
|
secondary · #15 | |
Leave-in
21 products
|
secondary · #34 | |
Mask / treatment
20 products
|
secondary · #21 | |
Heat protectant
11 products
|
secondary · #34 | |
Scalp treatment
4 products
|
secondary · #33 | |
Styler: smoothing cream
4 products
|
secondary · #44 | |
Styler: mousse
2 products
|
secondary · #22 | |
Co-wash
1 product
|
secondary · #9 | |
Finisher: serum
1 product
|
secondary · #21 |
3 more product types
| Product type | How common | Typical position on label ? |
|---|---|---|
Styler: curl cream
1 product
|
secondary · #45 | |
Styler: hairspray
1 product
|
secondary · #30 | |
Styler: volumizer
1 product
|
secondary · #26 |
| Product type | Products | Share of category | Median position | Earliest position | Band |
|---|---|---|---|---|---|
| Conditioner | 52 | 7% | 14 | 7 | secondary |
| Shampoo | 42 | 5% | 15 | 8 | secondary |
| Leave-in | 21 | 5% | 34 | 8 | secondary |
| Mask / treatment | 20 | 5% | 21 | 8 | secondary |
| Heat protectant | 11 | 8% | 34 | 8 | secondary |
| Scalp treatment | 4 | 3% | 33 | 22 | secondary |
| Styler: smoothing cream | 4 | 7% | 44 | 25 | secondary |
| Styler: mousse | 2 | 1% | 22 | 20 | secondary |
| Co-wash | 1 | 1% | 9 | 9 | secondary |
| Finisher: serum | 1 | 1% | 21 | 21 | secondary |
| Styler: curl cream | 1 | 1% | 45 | 45 | secondary |
| Styler: hairspray | 1 | 1% | 30 | 30 | secondary |
| Styler: volumizer | 1 | 2% | 26 | 26 | secondary |
No product-type differences have been researched yet — the reading below is computed from where it sits on the labels in our library.
Position footprint
Every listing in our library, by position on the label.
| Positions | Zone | Listings |
|---|---|---|
| 1-3 | Leading | 0 |
| 4-8 | Supporting | 13 |
| 9-15 | Secondary | 69 |
| 16-25 | Lower | 43 |
| 26+ | Trace | 61 |
How to read this
US labelling rules put ingredients above 1% in descending order of amount; below 1% they may be listed in any order.
So position tells you about relative amount only above that line, and we never convert a position into a percentage.
Who should pay attention
Conditional formulation guidance, scoped to a hair condition and to the positions where it is meaningful. It is not a conclusion about any finished product, and not a conclusion about you.
Amino acids are the smallest protein fraction and bind water as well, so they add far less stiffness than a hydrolysed protein does.
The lightest option in the protein family, but still protein — worth watching if protein reliably stiffens your hair.
Read from this ingredient’s chemical class. Where we have researched the ingredient itself, that reading replaces the class one.
Why it matters to shoppers
What this ingredient is evidence of, what it is not evidence of, and what our own method can and cannot tell you.
- the lightest protein option
- a light protein
- a rinse-clean feel
- help on very dry or damaged hair
- an exact safety score — we do not publish one, for any ingredient
- how a finished product performs by itself — that is the whole formula, not one line of it
- the exact percentage in a bottle — label position never converts into a number
- a secondary amino acid, listed below the main ingredients in our conditioners
- it was on the label of every product we counted — we read printed ingredient lists, not marketing copy
- that a product is right or wrong for you
We do not publish safety scores or hazard grades. Where a regulator has published a restriction or a use condition, we state it and cite it; otherwise we describe what the ingredient does and stop.
Commonly paired with
Ingredients that appear alongside this one most often in our library. Near-universal ingredients are excluded — they pair with everything and tell you nothing.
- Glycine · 74
- Cetyl Alcohol · 74
- Serine · 73
- Disodium EDTA · 72
- Arginine · 71
- Alanine · 69
- Phenylalanine · 67
- Valine · 67
- Isoleucine · 66
- Aspartic Acid · 66
The number beside a name is how many products in our library list both.
These ingredients tend to appear together to firm up damaged areas, soften the strand, and keep the formula stable.
Found in these products
The most prominent placements first. The badge is the position on that product’s own ingredient list.
Herbal Essences · Styler
Mango & Aloe Curl Refresh Mist
#4 on the label · $0.75/oz
Pantene · Leave-in
Gold Series Leave-on Detangling Milk
#5 on the label · $4.60/oz
Herbal Essences · Conditioner
Curl + Define Apricot Sulfate-Free Conditioner
#7 on the label · $0.74/oz
Herbal Essences · Conditioner
Full + Thick Passionflower Sulfate Free Conditioner
#7 on the label · $0.74/oz
Herbal Essences · Conditioner
Herbal Essences Argan Oil Repairing Conditioner, Color-Safe, For Damaged Hair
#7 on the label · $0.74/oz
Herbal Essences · Conditioner
Shine + Smooth Jojoba Oil Sulfate Free Conditioner
#7 on the label · $0.74/oz
Herbal Essences · Conditioner
Herbal Essences Classics Hydrate Conditioner with Coconut Water & Jasmine
#8 on the label · $0.38/oz
Herbal Essences · Conditioner
Moisture + Replenish Coconut Sulfate Free Conditioner
#8 on the label · $0.85/oz
Pantene · Heat protectant
Miracle Rescue 10-in-1 Multitasking Spray + Keratin
#8 on the label · $2.27/oz
Pantene · Mask / treatment
Miracle Rescue Intensive Bond Repair Mask with Melting Pro-V Pearls
#8 on the label · $1.29/oz
Pantene · Conditioner
Pantene Abundant & Strong Conditioner
#8 on the label · $1.95/oz
Pantene · Leave-in
Pro-V Miracles 3-in-1 Multi-Tasking Conditioner: Leave-in, Detangler and Heat Protectant
#8 on the label · $2.17/oz
Identity
What this entry is, and what our references call it.
Histidine
- CAS 71-00-1
- PubChem 6274
- histidine
- histidine hcl



For your hair?
Whether Histidine matters for your hair depends on your hair.
the 4th most-listed protein or amino acid in our libraryWhat this ingredient does, and where it sits on the labels we have researched.
A verdict on any product that contains it, and never a safety grade.
We do not physically test your hair. Everything above is read from the ingredient lists in our library and from published references — the consultation is what turns it into a plan.
References
Sourced Backed by a manufacturer or regulatory source.
This ingredient
- Manufacturer or regulatory PubChem — Compound identity: CID 6274, CAS 71-00-1, C6H9N3O2 · accessed 2026-08-28
How this page was made
- Every number above is counted from the ingredient lists in our own product library — 161 of 3889 researched products list this ingredient. Nothing on this page is written per ingredient.
- The dots are named levels read from an ingredient’s chemical class, charge, solubility, or where it sits on the labels we have — never a score.
- US labelling rules put ingredients above 1% in descending order of amount; below 1% they may be listed in any order. Position tells you about relative amount only above that line, and we never convert a position into a percentage.
- The prominence bands (leading, supporting, secondary) are the same ones the product pages use to read a single label, applied here to the median position across a category.
- We do not publish safety scores or hazard grades. Where a regulator has published a restriction or a use condition, we state it and cite it; otherwise we describe what the ingredient does and stop.
- Identifiers and references appear only when a published source is attached to this entry; where none is, the row is simply absent rather than filled in.
- This is cosmetic information, not medical advice, and nothing here diagnoses or treats a health condition.
- Entry last updated 2026-08-28. Product-page methodology: the product library.