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Side by side

Nioxin Hair Fall Defense Serum vs Nioxin Night density Rescue Serum

90% function match · 9 of the 10 functions we compared match Formula overlap 62%. Nioxin Hair Fall Defense Serum and Nioxin Night density Rescue Serum share 4 ingredients among each other's most prominent.

Based on your consultation

Which of these fits your hair?

We check your pattern, moisture need, scalp, fragrance tolerance, weight sensitivity and more against each formula — and say which one lines up.

Your profile at a glance

  • Your answers appear here
  • Your answers appear here
  • Your answers appear here
  • Your answers appear here

When each one is the right call

What each formula is built for, from its own ingredient list.

  • Hair Fall Defense Serum — protein-sensitive hair
  • Night density Rescue Serum — protein-sensitive hair

Side by side

Every trait, aligned

One row per trait, read from each product’s own ingredient list and record. A dash means we have not researched that field for that product — it is not a “no”.

Trait
Nioxin Hair Fall Defense Serum — front of package Nioxin

Hair Fall Defense Serum

  • Scalp treatment
  • Prestige
  • Sulfate-free
  • Silicone-free
Nioxin Night density Rescue Serum — front of package Nioxin

Night density Rescue Serum

  • Scalp treatment
  • Prestige
  • Sulfate-free
  • Silicone-free
Price, size & price per ounce
$28.04 2.3 oz · $16.97/oz
$38–50 2.3 oz · $21.10/oz
Value / price positioning
Upper-mid price for a scalp treatment $$$$$ Prestige tier · costs more than 70% of the 161 scalp treatments we’ve priced
Same job for less elsewhere $$$$$ Prestige tier · costs more than 76% of the 161 scalp treatments we’ve priced
Best for hair types
All types Nothing in the formula or the claims narrows this to one pattern. Your hair
All types Nothing in the formula or the claims narrows this to one pattern. Your hair
Moisture level Differs
None found No humectants found — nothing here pulls water into the hair. Your hair
High Humectants near the top — water-binding is a headline mechanism here. Your hair
Slip / detangling Same
Little Nothing here is built to reduce combing force. Your hair
Little Nothing here is built to reduce combing force. Your hair
Weight on hair Same
Light Water-first and light: unlikely to flatten fine hair. Your hair
Light Water-first and light: unlikely to flatten fine hair. Your hair
Fragrance
Prominent Fragrance sits in the first eight ingredients — a larger share of the formula. Your hair
Prominent Fragrance sits in the first eight ingredients — a larger share of the formula. Your hair
Protein Same
None No protein or amino acids in the list. Your hair
None No protein or amino acids in the list. Your hair
Silicone / wax buildup Same
None Nothing here needs a detergent wash to remove. Your hair
None Nothing here needs a detergent wash to remove. Your hair
Clarifying wash needed
Moderate Your hair
Moderate Your hair
Oils and butters Same
None No oils or butters in the list. Your hair
None No oils or butters in the list. Your hair
Hard-water defence Same
None No chelating agent in the list. Your hair
None No chelating agent in the list. Your hair
Formula completeness
out of 10
A simple formula
out of 10
A simple formula
Who should choose this
  • Protein-sensitive hairthat stiffens when protein is added
  • Fine hairthat flattens under most products
  • Silicone-free routinesno silicones appear in the list
  • Protein-sensitive hairthat stiffens when protein is added
  • Fine hairthat flattens under most products
  • Silicone-free routinesno silicones appear in the list
  • Easy to findsold through several channels
Why you might skip it
  • Scents bother youthis product carries a scent
  • Very dry or damaged hairit contains fast-drying alcohol
  • Vegan and cruelty-freeour record does not support both claims here
  • Scents bother youthis product carries a scent
  • Very dry or damaged hairit contains fast-drying alcohol
  • Vegan and cruelty-freeour record does not support both claims here
from the formula stated by the brand reported by reviewers Scale: 1 dot low · 5 dots high, within this product type.
More facts about each one
Type
Scalp treatmentserum
Scalp treatmentserum
Where to buy
Salons · Specialty beauty
Salons · Specialty beauty · Amazon
Free of
  • sulfate-free
  • silicone-free
  • protein-free
  • curly-method compatible
  • sulfate-free
  • silicone-free
  • protein-free
  • curly-method compatible
Cruelty-free
Not cruelty-free · PETA-listed
Not cruelty-free · PETA-listed
Scent
Scented, not described
Scented, not described

Facts as we recorded them. A dash means we have not researched that field for that product — it is not a "no".

The bottom line

The bottom line depends on your hair

Which of these two suits you is a question about your hair, not about them. The consultation answers it — and tells you what your routine needs around it.

Take the consultation

$49.00 once, for your consultation and hair profile. No subscription, no required purchases.

The detail behind the table

Where the readings above come from: the ingredient lists themselves, each brand’s claims checked against them, what owners report, and cost per ounce in context.

Shared and distinct ingredients

Shared and distinct ingredients

Computed from the ingredient lists as printed. "Shared" means both lists carry it; where it sits on each label is stated, because position is what tells you how much.

What both formulas carry

IngredientHair Fall Defense SerumNight density Rescue Serum
Alcohol Denat.
Drying
#13Below the 1% line
#1Leading
Water
Neutral
#2Leading
#2Leading
Caffeine
Active
#4Supporting
#3Leading
Fragrance
Fragrance
#6Below the 1% line
#5Below the 1% line
Lauric Acid
Stabilizes
#7Below the 1% line
#7Below the 1% line
PEG-40 Hydrogenated Castor Oil
Stabilizes
#8Below the 1% line
#8Below the 1% line
Hexyl Cinnamal
Fragrance
#11Below the 1% line
#16Below the 1% line
Limonene
Fragrance
#12Below the 1% line
#17Below the 1% line
Linalool
Fragrance
#14Below the 1% line
#13Below the 1% line

What only one of them carries

Hair Fall Defense Serum

Night density Rescue Serum

Full ingredient list — Hair Fall Defense Serum (16)
Full ingredient list — Night density Rescue Serum (25)

Claims check

What each brand says, against what each formula shows

Claims are quoted from each brand. We only mark one supported, partly supported, or conflicting when that product’s ingredient list actually speaks to it.

VerdictsHair Fall Defense SerumNight density Rescue Serum
Supported
1
1
Partly supported
0
0
Stated by brand
0
0
Potential conflict
0
0

Hair Fall Defense Serum

  • Free of parabens, sulfates, and colorantsSupportedGentler on colour and coils.

Night density Rescue Serum

  • Lightweight and non-greasySupportedLess likely to weigh hair down.

What owners say

What people report

Recurring themes our researchers wrote in their own words from sourced reviews. We do not store or scrape star ratings, and we never balance one product’s themes against another’s by inventing them.

Both praised for a light feel. Nioxin Hair Fall Defense Serum draws complaints about the scent; Nioxin Night density Rescue Serum draws complaints about irritation and the packaging.

Hair Fall Defense Serum

Several users find the serum light and non-greasy, with little residue on the hair.

US exact serum reviews; IDs1145071764 and1145071763; duplicate syndicated copies excluded.

A strong cologne-like fragrance is a recurring reason users dislike or discontinue the serum.

US exact-product reviewer accounts; promotional sampling appears in the corpus. Review IDs: 1221842646, 1220405157, 1194007192, 1193887057, 1165028641

Some reviewers report no noticeable improvement from the serum.

US exact-product reviewer accounts; promotional sampling appears in the corpus. Review IDs: 1145071947, 1145071837; corroborated by additional exact serum review1145071763.

Night density Rescue Serum

Users often find the liquid light and non-greasy for overnight application.

US exact-product reviewer accounts; promotional sampling appears in the corpus. Review IDs: 1172115598, 1171689932, 1171580825, 1169661644

Leaking bottles and difficult dispensing recur in packaging complaints.

US exact-product reviewer accounts; promotional sampling appears in the corpus. Review IDs: 1169690823, 1169555383, 1168103122, 1148458466

Some users report scalp tenderness, itching or a burning sensation.

US exact-product reviewer accounts; promotional sampling appears in the corpus. Review IDs: 1172271437, 1169507711, 1153761231

Reports of fuller-looking hair are mixed with reports of no visible difference after several weeks.

US exact-product reviewer accounts; promotional sampling appears in the corpus. Review IDs: 1175637429, 1171789190, 1172271437, 1169661644, 1148458337

Price check

Cost per ounce, in context

Cost per ounce against every product of this type we have priced, each at the size it is most often sold in. Value labels are computed from that percentile and from how many products that do the same job cost less; they are comparisons, not judgements about a brand.

$16.97/oz vs $21.10/oz — Nioxin Night density Rescue Serum costs about 1.2× more per ounce than Nioxin Hair Fall Defense Serum.

$1.25/oz median $7.25/oz $708.33/oz $16.97/oz Hair Fall Defense Serum $21.10/oz Night density Rescue Serum

Every mark sits on one distribution because these are compared against the same set: 161 scalp treatments with a computable unit price.

Value readHair Fall Defense SerumNight density Rescue Serum
Label
Upper-mid price for a scalp treatmentSits in the middle of the range for scalp treatments per ounce.
Same job for less elsewhereYou are paying above the range for a formula close to several lower-priced options.

Computed from cost per ounce against every product of this type we have priced, and from how many products that do the same job cost less. It is a comparison, not a judgement about the brand.

Compare with something else

Close formulas to each of these, as their own comparison pages.

Hair Fall Defense Serum vs Peppermint & Aloe Soothing Scalp TonicDesign Essentials · 99% function matchNight density Rescue Serum vs Scalp Care Soothing SerumMizani · 100% function matchHair Fall Defense Serum vs 100% Raw and Pure Batana OilSunny Isle · 99% function matchNight density Rescue Serum vs The Treatment Scalp SerumKilgourMD · 95% function matchHair Fall Defense Serum vs Hair & Scalp Oil With Vitamin ETaliah Waajid · 99% function matchNight density Rescue Serum vs Age Defense SerumNioxin · 95% function matchHair Fall Defense Serum vs Men's REVIVE+ Densifying Treatment FoamBosley · 92% function matchNight density Rescue Serum vs Scalp Revival Charcoal + Tea Tree Scalp TreatmentBriogeo · 95% function match

Hair Fall Defense Serum · Night density Rescue Serum · All scalp treatments in the library

How this page was made

  • This page is assembled from the same researched records the individual product pages render: identity, each ingredient list as printed, each brand's own claims, dated price observations, and review themes written in our researchers' own words. Nothing on it is written per comparison.
  • We do not rank these against each other. Which of them suits you depends on your hair, and that is what the consultation works out.
  • The formula similarity percentage is a stored, precomputed number: position-weighted overlap of the two ingredient lists blended with agreement on the attributes we derive. It measures how alike two formulas are, not how well either works.
  • The value band is a fixed label over two stored numbers: this product’s cost per ounce as a percentile of every product of this type we have priced, each at the size it is most often sold in, and how many products we score as doing the same job cost at least a quarter less per ounce.
  • The "Is this right for you?" panel reads only your own consultation answers, and it applies exactly the filters our recommendation engine applies. It is computed when you load the page and is never stored on it.
  • 12 sources were consulted across the products on this page.
  • Ingredient order tells you relative amount only above roughly 1%. Prices are observations on the dates shown and change without notice. We do not sell these products and take no placement fees.
  • This is cosmetic information, not medical advice, and nothing here diagnoses or treats a health condition.

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